Interferons (IFNs, /ˌɪntərˈfɪərɒn/ IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several...
62 KB (7,065 words) - 05:17, 28 June 2024
Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: Pegylated interferon-alpha-2a Pegylated interferon-alpha-2b...
2 KB (185 words) - 07:35, 11 September 2023
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
32 KB (2,851 words) - 23:22, 16 August 2024
Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...
56 KB (6,476 words) - 11:26, 29 July 2024
Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by...
23 KB (2,748 words) - 13:53, 21 January 2024
Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
7 KB (654 words) - 21:00, 23 April 2024
An interferon-stimulated gene (ISG) is a gene that can be expressed in response to stimulation by interferon. Interferons bind to receptors on the surface...
13 KB (1,530 words) - 20:52, 19 April 2024
The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...
24 KB (2,932 words) - 03:26, 14 June 2024
Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). Interferon regulatory...
10 KB (1,098 words) - 23:10, 30 March 2024
Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon...
24 KB (2,894 words) - 01:36, 26 August 2023