The δ-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR or DOP, is an inhibitory 7-transmembrane G-protein...
28 KB (3,262 words) - 06:56, 10 July 2024
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
40 KB (4,427 words) - 12:37, 12 January 2024
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
22 KB (2,424 words) - 08:47, 18 May 2024
An opioid antagonist, or opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors. Naloxone and naltrexone...
11 KB (1,340 words) - 14:34, 24 July 2024
Opioid peptides or opiate peptides are peptides that bind to opioid receptors in the brain; opiates and opioids mimic the effect of these peptides. Such...
19 KB (1,419 words) - 18:28, 15 March 2024
relief. As a class of substances, they act on opioid receptors to produce morphine-like effects. The terms 'opioid' and 'opiate' are sometimes used interchangeably...
222 KB (19,669 words) - 18:52, 20 August 2024
The κ-opioid receptor or kappa opioid receptor, abbreviated KOR or KOP for its ligand ketazocine, is a G protein-coupled receptor that in humans is encoded...
67 KB (7,676 words) - 03:02, 15 August 2024
(~60%) with the ‘classical’ opioid receptors μ-OP (MOP), κ-OP (KOP), and δ-OP (DOP), it possesses little or no affinity for opioid peptides or morphine-like...
28 KB (3,378 words) - 13:44, 13 August 2024
Carfentanil (category Mu-opioid receptor agonists)
values (Ki) of 0.051 nM for the μ-opioid receptor, 4.7 nM for the δ-opioid receptor, and 13 nM for the κ-opioid receptor in rat brain. Thus, carfentanil...
22 KB (2,039 words) - 06:04, 14 July 2024
μ-opioid receptor agonist and a peripherally selective μ-, κ-, and δ-opioid receptor antagonist. Cebranopadol (GRT-6005) – non-selective μ-opioid receptor...
18 KB (1,274 words) - 09:53, 9 January 2024