ACT-539313 is an orexin antagonist medication which is under development for the treatment of binge eating disorder and was previously under development...
6 KB (402 words) - 20:39, 1 December 2023
Daridorexant (redirect from ACT-541468)
A and orexin B, are involved in the regulation of sleep–wake cycles and act to promote wakefulness. Deficiency of orexin signaling is thought to be the...
48 KB (4,078 words) - 11:27, 24 July 2024
sleep apnea, up to phase 2 – half-life 1.5–3 hours ACT-335827 – selective OX1 antagonist Almorexant (ACT-078573) – dual OX1 and OX2 antagonist – development...
19 KB (1,978 words) - 11:32, 1 May 2024
lemborexant in 2019 and daridorexant in 2022. Development of almorexant (ACT-078573) and filorexant (MK-6096) was discontinued, while seltorexant (MIN-202...
94 KB (8,941 words) - 16:56, 16 September 2024
(YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) RTIOX-276 SB-334867 SB-408124 Suvorexant TCS-1102 Tebideutorexant (JNJ-61393215)...
21 KB (1,687 words) - 09:07, 5 September 2024
antagonist JNJ-10397049 – selective OX2 receptor antagonist Nivasorexant (ACT-539313) – selective OX1 receptor antagonist RTIOX-276 – selective OX1 receptor...
13 KB (1,234 words) - 02:29, 15 August 2024
(YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) RTIOX-276 SB-334867 SB-408124 Suvorexant TCS-1102 Tebideutorexant (JNJ-61393215)...
7 KB (498 words) - 08:59, 15 September 2024
(YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) RTIOX-276 SB-334867 SB-408124 Suvorexant TCS-1102 Tebideutorexant (JNJ-61393215)...
5 KB (301 words) - 01:02, 17 September 2024
(YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) RTIOX-276 SB-334867 SB-408124 Suvorexant TCS-1102 Tebideutorexant (JNJ-61393215)...
5 KB (653 words) - 05:33, 8 December 2023
(YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) RTIOX-276 SB-334867 SB-408124 Suvorexant TCS-1102 Tebideutorexant (JNJ-61393215)...
54 KB (6,141 words) - 03:36, 18 August 2024