humans is encoded by the ADAM12 gene. ADAM12 has two splice variants: ADAM12-L, the long form, has a transmembrane region and ADAM12-S, a shorter variant...

protease enzyme whose catalytic mechanism involves a metal. An example is ADAM12 which plays a significant role in the fusion of muscle cells during embryo...

Fusion in humans is aided by a set of metalloproteinases coded for by the ADAM12 gene, and a variety of other proteins. Fusion involves recruitment of actin...

HGNC:216 Q13443 254 ADAM10 HGNC:188 O14672 255 ADAM11 HGNC:189 O75078 256 ADAM12 HGNC:190 O43184 257 ADAM15 HGNC:193 Q13444 258 ADAM17 HGNC:195 P78536 259...

(2005). "Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity". Proc. Natl. Acad. Sci. U.S.A. 102 (8): 3058–63...

Satoshi Ansai, Masato Kinoshita and Atsuko Sehara-Fujisawa. 58 409-421 2016 ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage...

region of chromosome 17q21 previously defined by tumor deletion mapping. ADAM12 ADAM12, a metalloprotease that binds insulin growth factor binding protein-3...

IGF1R and promote cell survival. IGFBP3 has been shown to interact with: ADAM12 ADAM28 COL1A1 FN1 IGFALS IGF1, IGF2 HSPA5 Humanin PLG RXRA TF KPNB1 PRKDC...

have been implicated in the proteolytic cleavage of LRP1 such as ADAM10, ADAM12, ADAM17 and MT1-MMP. LRP1 is also continuously endocytosed from the membrane...

PMID 12477932. Mori S, Tanaka M, Nanba D, et al. (2003). "PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal...