Alpha-protein kinase 1 is an enzyme that in humans is encoded by the ALPK1 gene. Unlike most eukaryotic kinases, alpha kinases, such as LAK, recognize...

autosomal dominant manner and caused by heterozygous missense mutations in the ALPK1 gene, an innate immune sensor for bacterial sugars. While the initial descriptions...

Kozycki CT, Kodati S, Huryn L, et al. (2022). "Gain-of-function mutations in ALPK1 cause an NF-κB-mediated autoinflammatory disease: functional assessment...

HGNC:13743 Q9BYJ1 596 ALPG HGNC:441 P10696 597 ALPI HGNC:437 P09923 598 ALPK1 HGNC:20917 Q96QP1 599 ALPK2 HGNC:20565 Q86TB3 600 ALPK3 HGNC:17574 Q96L96...

response activation is primarily driven by the use of ADP-heptoses to activate ALPK1, by a C. jejuni infection Neutrophil granulocytes use phagocytosis to combat...

24 SAC cases or gain-of-function (i.e. gene-activating) mutations in the ALPK1 gene in 7 of 16 SA and 4 of 14 SAC cases. The two mutations are mutually...

Fukuda M, Sawabe M (June 2013). "Identification of chromosome 3q28 and ALPK1 as susceptibility loci for chronic kidney disease in Japanese individuals...