• Thumbnail for Amyloid plaques
    Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
    31 KB (3,370 words) - 05:18, 1 May 2024
  • Thumbnail for Amyloid beta
    Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
    43 KB (4,769 words) - 20:19, 27 June 2024
  • Thumbnail for Amyloid
    Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
    60 KB (6,532 words) - 04:25, 19 July 2024
  • and cingulate gyrus. Both amyloid plaques and neurofibrillary tangles are clearly visible by microscopy in AD brains. Plaques are dense, mostly insoluble...
    65 KB (7,761 words) - 08:45, 1 July 2024
  • Thumbnail for Amyloid-beta precursor protein
    generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose amyloid fibrillar form is the primary component of amyloid plaques found...
    50 KB (5,683 words) - 05:16, 29 June 2024
  • Notably, amyloid plaques have been hypothesized to counteract this BBB leakage. However, upon the administration of antibodies, these plaques are targeted...
    9 KB (780 words) - 01:16, 3 January 2024
  • Thumbnail for Alzheimer's disease
    of abnormally folded amyloid beta protein into amyloid plaques, and tau protein into neurofibrillary tangles in the brain. Plaques are made up of small...
    179 KB (18,931 words) - 23:05, 14 July 2024
  • Thumbnail for Atherosclerosis
    of atherosclerotic changes is similar to that in the development of amyloid plaques in the brain and that of age spots on the skin. Misrepair-accumulation...
    100 KB (11,153 words) - 15:25, 13 July 2024
  • radiotracer developed for routine clinical application to visualize β-amyloid plaques in the brain. It is a fluorine-18 (18F)-labeled stilbene derivative...
    17 KB (1,509 words) - 06:21, 1 July 2024
  • Thumbnail for Cerebral amyloid angiopathy
    Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
    18 KB (1,768 words) - 23:46, 18 June 2024