Bivalirudin, sold under the brand names Angiomax and Angiox, among others, is a specific and reversible direct thrombin inhibitor (DTI). Chemically, it...

that bivalirudin is non-inferior compared to heparin and that bivalirudin is associated with a lower rate of bleeding. Unlike the hirudins, bivalirudin is...

this purpose; mainly used are danaparoid, fondaparinux, argatroban, and bivalirudin. While purified heparin was first used in humans in the 1930s, HIT was...

to direct thrombin inhibitors including dabigatran, argatroban, and bivalirudin. After separating the plasma from the whole blood by centrifugation,...

members of this class include the bivalent drugs hirudin, lepirudin, and bivalirudin and the monovalent drugs argatroban and dabigatran. An oral direct thrombin...

argatroban. Other "blood thinners" sometimes used in this setting include bivalirudin and fondaparinux. Platelet transfusions are not routinely used to treat...

example, the anticoagulant drugs, hirudin and its synthetic congener, bivalirudin, are based on saliva chemistry of the leech, Hirudo medicinalis. Used...

members are already in clinical use (such as lepirudin, argatroban, bivalirudin and dabigatran). Also in clinical use are other small molecular compounds...

desirudin (Revasc/Iprivask) – differs by removal of sulfate group on Tyr63 bivalirudin – peptide fragment Several other direct thrombin inhibitors are derived...

evidence that REG1 reduced ischaemic events or bleeding compared with bivalirudin. Lincoff, A. Michael; Mehran, Roxana; Povsic, Thomas J.; Zelenkofske...