c-Jun N-terminal kinases (JNKs), were originally identified as kinases that bind and phosphorylate c-Jun on Ser-63 and Ser-73 within its transcriptional...
14 KB (1,626 words) - 20:50, 30 May 2024
mammalian MAPK family of kinases includes three subfamilies: Extracellular signal-regulated kinases (ERKs) c-Jun N-terminal kinases (JNKs) p38 mitogen-activated...
46 KB (5,492 words) - 14:52, 20 August 2024
the c-jun target genes. Therefore, regulation of c-jun activity can be achieved through N-terminal phosphorylation by the Jun N-terminal kinases (JNKs)...
45 KB (5,452 words) - 05:07, 13 July 2024
neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in...
11 KB (1,348 words) - 06:45, 11 March 2024
(SU-3327) is an experimental drug that acts as an enzyme inhibitor of c-Jun N-terminal kinase (JNK). Originally, it was researched for the treatment of diabetes...
7 KB (626 words) - 07:37, 1 April 2024
MAPK8 (redirect from Mitogen-activated protein kinase 8)
(December 1997). "MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases". J. Biol. Chem. 272 (51): 32056–60. doi:10.1074/jbc...
16 KB (1,781 words) - 00:37, 15 June 2024
protein kinases (MAPK). These include extracellular signal-regulated kinase, p38 mitogen-activated protein kinases, and c-Jun N-terminal kinases. The synthetic...
67 KB (7,676 words) - 03:02, 15 August 2024
follows: IAA/HRP activates p38 mitogen-activated protein kinases and c-Jun N-terminal kinases. It induces caspase-8 and caspase-9, which results in caspase-3...
26 KB (2,766 words) - 00:37, 15 May 2024
Yamaguchi N, Yokoyama KK (March 2009). "Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated...
27 KB (2,716 words) - 18:23, 1 August 2024
affecting its ATPase or isopeptidase activities. MG132 activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis. MG132 also inhibits NF-κB activation...
5 KB (374 words) - 05:47, 29 November 2023