The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL-2RG, is a cytokine receptor sub-unit that is common to...
16 KB (2,092 words) - 14:33, 22 June 2024
cases have yet been seen in trials of ADA-SCID, which does not involve the gamma c gene that may be oncogenic when expressed by a retrovirus. From the treatments...
34 KB (3,270 words) - 01:33, 14 August 2024
located on the X-chromosome. This gene encodes the interleukin receptor common gamma chain protein, which is a cytokine receptor sub-unit that is part of the...
36 KB (4,335 words) - 20:14, 12 July 2024
IL2RA (redirect from Interleukin-2 receptor alpha chain)
Interleukin-2 receptor, consisting of alpha (IL2RA), beta (IL2RB) and the common gamma chain (IL2RG). As the name indicates, this receptor interacts with Interleukin-2...
23 KB (2,548 words) - 19:00, 2 April 2024
cytokines like IL-2R or IL-15 and requires dimerization with the common gamma chain (γc) in order to bind IL-21. When bound to IL-21, the IL-21 receptor...
23 KB (2,936 words) - 15:14, 9 April 2024
Fibrinogen gamma chain, also known as fibrinogen gamma gene (FGG), is a human gene found on chromosome 3. The protein encoded by this gene is the gamma component...
4 KB (471 words) - 06:11, 25 December 2023
Interleukin-7 receptor-α (IL7Rα), DCLRE1C-Artemis, RMRP-CHH, DNA-Ligase IV, common gamma chain, WHN-FOXN1, ZAP-70 and complete DiGeorge syndrome. It is fatal without...
5 KB (515 words) - 14:37, 27 October 2023
either common gamma chain (γc, forming the type I IL4 receptor) or with IL-13Rα1 (forming the type II IL4 receptor). This gene encodes the alpha chain of...
7 KB (774 words) - 19:18, 19 April 2024
through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes...
39 KB (4,458 words) - 06:59, 3 June 2024
IL-7 receptor-α, CD127, and common-γ chain, CD132. In the naive state, T cells are thought to require the common-gamma chain cytokines IL-7 and IL-15 for...
9 KB (1,147 words) - 07:16, 18 July 2023