Coumermycin A1 is an aminocoumarin. Its main target is the ATPase site of the DNA gyrase GyrB subunit. Chemically induced dimerization Heide L (2009)....
4 KB (129 words) - 19:01, 8 January 2024
that inhibit gyrase are: The aminocoumarins (including novobiocin and Coumermycin A1), which work by competitive inhibition of energy transduction of DNA...
15 KB (1,871 words) - 08:04, 9 August 2024
Actinomycetia. Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s (then called streptonivicin)...
21 KB (2,266 words) - 08:08, 24 June 2024
from soil in Hokkaido in Japan. Streptomyces rishiriensis produces coumermycin A1, notomycin, 2-chloroadenosine, phosphophenylalanarginine and lactonamycin...
7 KB (734 words) - 21:36, 12 April 2024
future. Aminocoumarins (Fig. 6), such as novobiocin, clorobiocin and coumermycin A1, are natural products from Streptomyces that inhibit the ATPase reaction...
57 KB (6,173 words) - 00:11, 11 December 2023
producers: two type II topoisomerase genes confer resistance against coumermycin A1 and clorobiocin". Antimicrob Agents Chemother. 47 (3): 869–77. doi:10...
6 KB (670 words) - 05:05, 19 December 2023
NSC 128285 35959-87-6 C53H52O22 venicoside E 208707-91-9 C53H55N5O20 coumermycin A2 3130-60-7 C53H56N5O10P 5-hydroxy-dc CEP 197579-70-7 C53H58O17 thielocin...
47 KB (16 words) - 08:43, 18 August 2022