Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. It is the primary nuclease that executes the...

romanized: sakartvelos sakhelmts'ipo drosha), also known as the Five-Cross Flag (ხუთჯვრიანი დროშა, khutjvriani drosha), is one of the national symbols of...

enzyme Drosha, a protein that cuts RNA, to form the Microprocessor complex. In this complex, DGCR8 orients the catalytic RNase III domain of Drosha to liberate...

melanogaster and Caenorhabditis elegans, the protein is known as Pasha (partner of Drosha). It is a required component of the RNA interference pathway. The subunit...

animal cells. The complex is minimally composed of the ribonuclease enzyme Drosha and the dimeric RNA-binding protein DGCR8 (also known as Pasha in non-human...

suppression of the organism. Class 3 RNase III Class 3 RNases III include the Drosha family of enzymes known to function in maturation of precursors to microRNA...

and Drosha proteins. However some microRNAs, mirtrons, are known to be derived from introns via a different pathway which bypasses Pasha and Drosha. Some...

proteins Drosha and Pasha, which are critical to canonical microRNA biogenesis. It is the only animal thus far reported to be missing Drosha. MicroRNAs...

stem-loop structures known as pre-miRNA in the cell nucleus by the enzymes Drosha and Pasha. After being exported, it is then processed to mature miRNAs in...

family, like DROSHA, play a role in processing precursor rRNAs, contributing to the assembly of functional ribosomes. DICER and DROSHA also from the...