known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene. The...

Docking proteins such as GRB2 contain an SH2 domain that binds to the phosphotyrosine residues of the activated receptor. GRB2 binds to the guanine nucleotide...

GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. GAB2 is a docking protein with a conserved...

GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. The protein encoded by this gene is a member of the IRS1-like...

GRB2 associated binding protein 3 is a protein that in humans is encoded by the GAB3 gene. This gene is a member of the GRB2-associated binding protein...

unable to bind PI3K but is able to bind Grb2 and Gads, gives little NF-κB or IL-2, suggesting that those Grb2 and Gads are unable to compensate for the...

found on Grb2 proteins, allowing them to bind Receptor Tyrosine Kinases (RTKs), and also on SOS proteins allowing them to interact with Grb2. This brings...

adaptor protein Grb2 forms a complex with Sos by the Grb2 SH3 domain. Grb2 (or the Grb2/Sos complex) is recruited to the membrane by the Grb2 SH2 domain binding...

substrate 2 GAB2 – GRB2-associated binding protein 2 GRAP – GRB2-related adaptor protein GRAP2 – GRB2-related adaptor protein 2 GRB2 – Growth factor receptor-bound...

Adenylyl cyclase Phospholipase C Phospholipase A guanylate cyclase RasGEF (Grb2-Sos) Second messenger cAMP (cyclic adenosine monophosphate) IP3; DAG; Ca2+...