The globins are a superfamily of heme-containing globular proteins, involved in binding and/or transporting oxygen. These proteins all incorporate the...

beta (beta globin, β-globin, haemoglobin beta, hemoglobin beta) is a globin protein, coded for by the HBB gene, which along with alpha globin (HBA), makes...

important regulatory molecule nitric oxide bound to a thiol group in the globin protein, releasing it at the same time as oxygen. Hemoglobin is also found...

of two ζ globins (zeta globins) and two ε globins (epsilon globins) (ζ2ε2) Hb Gower-2, composed of two alpha globins and two epsilon globins (α2ε2) Hb...

underproduction of HbA (adult hemoglobin). The imbalance of alpha to beta globin chains leads to ineffective erythropoiesis, increased hemolysis, and deranged...

The human β-globin locus is composed of five genes located on a short region of chromosome 11, responsible for the creation of the beta parts (roughly...

Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral βΑ-T87Q -Globin Vector (LentiGlobin BB305 Drug Product)". Blood. 124 (21): 549. doi:10.1182/blood...

manner and is tissue-specific, as seen in the selective expression of β-globin genes in erythroid cells. Expression levels of genes can be modified by...

common adult form of hemoglobin and is composed of two alpha and two delta-globin subunits. This hemoglobin makes up 1-3% of hemoglobin in adults. Hemoglobin...

into a roughly spherical shape. The term globin can refer more specifically to proteins including the globin fold. The term globular protein is quite...