to achieve glycorandomization/diversification have been developed: an enzyme-based strategy referred to as 'chemoenzymatic glycorandomization' and a chemoselective...
13 KB (1,507 words) - 17:13, 30 March 2022
non-native sugar nucleotides has enabled a process referred to as glycorandomization where these sugar nucleotide libraries serve as donors for permissive...
8 KB (903 words) - 13:38, 24 October 2024
mustard. Carbohydrate Carbohydrate chemistry Chemical glycosylation Glycorandomization Glycosylation Natural products Brito-Arias, Marco (2007). Synthesis...
16 KB (1,893 words) - 04:59, 27 August 2024
anomeric kinases serve as a cornerstone for in vitro and in vivo glycorandomization. Recently, the roles of active site residues in human galactokinase...
14 KB (1,495 words) - 18:04, 11 August 2024
phenomenon that could be exploited for sugar nucleotide synthesis and 'glycorandomization'. The structures of all four glycosyltransferases were also reported...
16 KB (1,506 words) - 18:06, 10 February 2024
chemically closely related group of parasiticides. Avermectin/ivermectin glycorandomization Yoon, Y. J.; Kim, E.-S.; Hwang, Y.-S.; Choi, C.-Y. (2004). "Avermectin:...
16 KB (1,799 words) - 22:49, 11 July 2024
to Natural Product Glycodiversification: Pathway Engineering and Glycorandomization". Comprehensive Glycoscience. pp. 373–396. doi:10.1016/B978-044451967-2/00040-4...
4 KB (366 words) - 08:32, 16 February 2024
generate libraries of differentially glycosylated analogs through glycorandomization. Both the vancomycin aglycone and the complete vancomycin molecule...
83 KB (8,190 words) - 02:52, 25 October 2024
cancer has been restricted by its narrow therapeutic index. Digitoxin glycorandomization led to the discovery of novel digitoxigenin neoglycosides which displayed...
14 KB (1,277 words) - 18:23, 29 October 2024
context of drug discovery and drug development (a process known as glycorandomization). Suitable enzymes can be isolated from natural sources or produced...
14 KB (1,566 words) - 05:14, 19 September 2024