factor protein 1 (HSF 1) is a protein that in humans is encoded by the HSF1 gene. HSF1 is highly conserved in eukaryotes and is the primary mediator of transcriptional...

shock factor 1 (HSF1). There are four different transcription factors found in vertebrates (HSF 1–4) where the main regulator of HSPs is HSF1, while σ32 is...

to incorporate multiple transcriptional factors. Utilizing MS2, p65, and HSF1 proteins, dCas9-SAM system recruits various transcriptional factors working...

expression. Recently it was discovered that HSF1 is a powerful multifaceted modifier of carcinogenesis. HSF1 knockout mice show significantly decreased...

in humans is encoded by the HSF2 gene. HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and...

"Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway". PLOS Biology. 17 (3): e2006966. doi:10.1371/journal.pbio...

ENSG00000128709 Homeodomain Known motif – High-throughput in vitro [410] TTTTATKRC HSF1 ENSG00000185122 HSF Known motif – High-throughput in vitro [411] VGAABVTTCBVGAW...

molecules that are activated by JNK include c-Jun, ATF2, ELK1, SMAD4, p53 and HSF1. The downstream molecules that are inhibited by JNK activation include NFAT4...

dissociation of inactive HSF1 from complexes with heat shock proteins Hsp40/Hsp70 and Hsp90. With help from the ncRNA hsr1, HSF1 then trimerizes, becoming...

chaperone proteins, inhibition of proteasome function and activation of HSF1, which triggers the heat shock response. The available evidence indicates...