Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. The disease presents with progressive...

Spastic paraplegia 15 (SPG15) is a form of hereditary spastic paraplegia that commonly becomes apparent during childhood or adolescence (e.g. between ages...

Spastic paraplegia 31 is a rare type of hereditary spastic paraplegia which is characterized by sensation anomalies of the lower extremities. People with...

Warburg Micro syndrome (WARBM), a Complex Hereditary Spastic Paraplegia or RAB18 Deficiency, is a rare autosomal recessive genetic disorder characterized...

basal ganglia on magnetic resonance imaging. Hereditary spastic paraplegias are a diverse class of hereditary degenerative spinal cord disorders characterized...

depending on whether additional clinical features are present besides spastic paraplegia, such as optic atrophy, ataxia, peripheral neuropathy, extrapyramidal...

types of symptoms. Damage to the upper motor neuron typically causes spasticity including stiffness and increased tendon reflexes, and/or clonus, while...

Spastic paraplegia 6 is a rare type of hereditary spastic paraplegia characterized by muscle tone and bladder anomalies associated with pes cavus and specific...

neuron disease Hereditary motor and sensory neuropathies Spinal muscular atrophies Charcot–Marie–Tooth disease Hereditary spastic paraplegia Irobi, J; De...

that is indicative of ALS, and absence of family history for Hereditary Spastic Paraplegia (HSP) and ALS. Imaging studies to rule out structural or demyelinating...