3-Hydroxy-3-methylglutaryl-CoA lyase deficiency, (HMGCLD) also known as HMGCL deficiency, HMG-CoA lyase deficiency, or hydroxymethylglutaric aciduria,...
20 KB (1,860 words) - 08:08, 20 August 2024
3-Hydroxy-3-methylglutaryl-CoA lyase (or HMG-CoA lyase) is an enzyme (EC 4.1.3.4 that in human is encoded by the HMGCL gene located on chromosome 1. It...
7 KB (812 words) - 15:51, 12 February 2024
biochemistry, hydroxymethylglutaryl-CoA synthase or HMG-CoA synthase EC 2.3.3.10 is an enzyme which catalyzes the reaction in which acetyl-CoA condenses with...
9 KB (877 words) - 20:48, 6 June 2024
variety of end-products, including cholesterol in humans. HMG-CoA lyase breaks it into acetyl CoA and acetoacetate. Steroidogenic enzyme Sarkar DP (2015)....
8 KB (959 words) - 23:27, 8 December 2021
congestion Hepatic failure Hereditary ACTH resistance HMG-CoA lyase deficiency Hydroxymethylglutaryl-CoA lyase deficiency Hyperinsulinism-hyperammonemia syndrome...
21 KB (1,265 words) - 01:46, 22 December 2023
List of EC numbers (EC 4) (redirect from Phosphorus-oxygen lyases)
isocitrate lyase EC 4.1.3.2: Now EC 2.3.3.9, malate synthase EC 4.1.3.3: N-acetylneuraminate lyase EC 4.1.3.4: hydroxymethylglutaryl-CoA lyase EC 4.1.3...
62 KB (7,931 words) - 19:04, 4 January 2024
Dyslipidemia (section ATP citrate lyase inhibitors)
or if they are not tolerated. Statins competitively inhibit hydroxymethylglutaryl (HMG) CoA reductase which is used in the biosynthesis of cholesterol...
30 KB (2,967 words) - 22:36, 25 September 2024
or hydroxymethylglutaryl-CoA (HMG-CoA) respectively. MC-CoA is then converted by the enzyme methylcrotonyl-CoA carboxylase to methylglutaconyl-CoA (MG-CoA)...
106 KB (9,982 words) - 15:37, 7 January 2024
or hydroxymethylglutaryl-CoA (HMG-CoA) respectively. MC-CoA is then converted by the enzyme methylcrotonyl-CoA carboxylase to methylglutaconyl-CoA (MG-CoA)...
27 KB (4,132 words) - 00:11, 7 September 2024
> 1 in 75,000 Hydroxymethylglutaryl lyase deficiency (HMG) < 1 in 100,000 Isovaleric acidemia (IVA) < 1 in 100,000 3-Methylcrotonyl-CoA carboxylase deficiency...
7 KB (716 words) - 06:19, 9 June 2024