(FK506), which inhibit the prolyl isomerase activity of the immunophilins. The drug-immunophilin complexes (CsA-CyP and FK506-FKBP) bind to calcineurin, which...
6 KB (638 words) - 08:00, 3 June 2024
groups:[citation needed] glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs In pharmacologic (supraphysiologic) doses, glucocorticoids...
29 KB (3,337 words) - 00:02, 9 August 2024
(December 1992). "Structural and evolutionary relationships among the immunophilins: two ubiquitous families of peptidyl-prolyl cis-trans isomerases". FASEB...
8 KB (880 words) - 18:46, 25 March 2024
exhibits protein phosphatase 2C enzymatic activity, and the dual-family immunophilins that occur in a number of unicellular organisms (such as protozoan parasites...
19 KB (2,305 words) - 05:22, 15 May 2024
is helpful with autoimmune diseases|, Alternatively, inhibitors of immunophilins more specifically target T lymphocyte activation, the process by which...
59 KB (6,128 words) - 05:06, 8 July 2024
that is responsible for the interaction with co-factors such as the immunophilins FKBP51 and FKBP52, the stress induced phosphoprotein 1 (Sti1/Hop), cyclophilin-40...
51 KB (5,537 words) - 09:56, 13 June 2024
around the heat shock protein 90 (HSP90), containing p23 protein, and immunophilin, and located in majority in cytoplasm and partially in nucleus. In the...
75 KB (7,245 words) - 18:33, 11 August 2024
(may be pseudogene): FKBP1C Pseudogenes in humans: LOC541473; FKBP9L; Immunophilins Siekierka JJ, Hung SH, Poe M, Lin CS, Sigal NH (October 1989). "A cytosolic...
6 KB (656 words) - 18:45, 22 August 2023
cytoplasm and form multiprotein complexes with heat shock proteins (HSPs), immunophilins, and other chaperones such as src, and p23. The GR acts in a ligand-dependent...
57 KB (5,140 words) - 21:09, 11 July 2024
Stensgard B, Toft D (January 1996). "The involvement of p23, hsp90, and immunophilins in the assembly of progesterone receptor complexes". The Journal of...
13 KB (1,373 words) - 07:05, 20 May 2024