Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate...
33 KB (3,330 words) - 07:05, 3 April 2024
IDH2 (redirect from Isocitrate dehydrogenase 2)
Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases are enzymes that catalyze...
17 KB (2,094 words) - 06:10, 8 August 2024
the isocitrate/isopropylmalate dehydrogenase family is a protein family consisting of the evolutionary related enzymes isocitrate dehydrogenase, 3-isopropylmalate...
4 KB (388 words) - 15:47, 28 April 2022
Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene on chromosome 2. Isocitrate dehydrogenases catalyze...
30 KB (3,164 words) - 06:13, 8 August 2024
forms of glioma. Vorasidenib is a dual mutant isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 (mIDH1/2) inhibitor. The most common adverse...
16 KB (1,106 words) - 19:43, 29 October 2024
all dehydrogenases in the citric acid cycle with the exception of succinate dehydrogenase, inhibits pyruvate dehydrogenase, isocitrate dehydrogenase, α-ketoglutarate...
56 KB (6,064 words) - 05:23, 21 October 2024
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene. Isocitrate dehydrogenases...
14 KB (1,667 words) - 17:09, 3 December 2023
dependent isocitrate dehydrogenase, NAD isocitrate dehydrogenase, NAD-linked isocitrate dehydrogenase, NAD-specific isocitrate dehydrogenase, NAD isocitric...
5 KB (466 words) - 14:35, 26 August 2023
Caldococcus (section Isocitrate Dehydrogenase Research)
understand the characteristics of the isocitrate dehydrogenase ancestral protein. The mutant isocitrate dehydrogenase genes contain inferred ancestral sequences...
9 KB (990 words) - 18:07, 25 April 2024
phosphorylation of isocitrate dehydrogenase, which has a much higher affinity for isocitrate as compared to ICL. Deactivation of isocitrate dehydrogenase by phosphorylation...
22 KB (2,451 words) - 04:18, 23 September 2024