An isopeptidase is a protease enzyme that hydrolyzes isopeptide bonds, or amide bonds that occur outside the main chain in a polypeptide chain. Isopeptide...
3 KB (349 words) - 05:24, 18 July 2023
strains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. MG132 activates c-Jun N-terminal kinase (JNK1), which initiates...
5 KB (374 words) - 05:47, 29 November 2023
314. PMID 8723724. "Entrez Gene: USP5 ubiquitin specific peptidase 5 (isopeptidase T)". Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li...
8 KB (997 words) - 17:15, 14 December 2023
shown to be a sensitive substrate for UCH-L3 (Km = 0.039 μM) and for Isopeptidase-T (Km = 0.17-1.4 μM), and is particularly useful for studying deubiquitinylating...
2 KB (274 words) - 08:53, 18 May 2024
RJ (2017). "Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11". Nature Chemical Biology. 13 (5): 486–493. doi:10.1038/nchembio...
18 KB (2,482 words) - 05:06, 15 February 2024
S2CID 2856065. "Entrez Gene: USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)". D'Andrea A, Pellman D (1999). "Deubiquitinating enzymes: a new...
4 KB (456 words) - 22:25, 3 March 2023
1113–22. PMID 11884512. Li SJ, Hochstrasser M (March 2003). "The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization...
3 KB (293 words) - 16:15, 26 August 2023
types of reactions including deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. Unlike other members of the transglutaminase family, tTG...
35 KB (3,913 words) - 23:30, 30 May 2024
intracellular targets. These conjugates can be reversed by UBL-specific isopeptidases that have similar mechanisms to that of the deubiquitinating enzymes...
98 KB (11,068 words) - 18:25, 16 July 2024
also known as UBP43, is a type I interferon receptor repressor and an isopeptidase. In humans, it is encoded by the USP18 gene. USP18 is induced by the...
18 KB (1,884 words) - 05:57, 26 April 2022