LMO2, RBTNL1, RBTN2, RHOM2, LIM Domain Only Protein 2, TTG2, and T-Cell Translocation Protein 2, is a protein which in humans is encoded by the LMO2 gene...
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close proximity of the inserted gene to the LMO2 promoter, which controls the transcription of the LMO2 proto-oncogene. Hybrid Fusion protein Gene pool...
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"Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4". EMBO J. 22 (9): 2224–33. doi:10.1093/emboj/cdg196. ISSN 0261-4189...
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HGNC:26683 Q8N9Z9 8792 LMNTD2 HGNC:28561 Q8IXW0 8793 LMO1 HGNC:6641 P25800 8794 LMO2 HGNC:6642 P25791 8795 LMO3 HGNC:6643 Q8TAP4 8796 LMO4 HGNC:6644 P61968 8797...
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disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted. LMO1 has been shown to interact with GATA3 and TAL1. GRCh38:...
9 KB (1,258 words) - 20:36, 27 December 2023
PMID 15958283. Han C, Liu H, Liu J, et al. (2005). "Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex"...
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respectively. Lmo2 is associated with T-cell leukemias, and is also essential to erythropoiesis in early developmental stages, as Lmo2 knockout mice experience...
26 KB (3,172 words) - 15:28, 13 May 2024
Schmidt M, McCormack MP, Wulffraat N, Leboulch P, et al. (October 2003). "LMO2-associated clonal T cell proliferation in two patients after gene therapy...
60 KB (8,340 words) - 05:00, 22 July 2024
leukemia due to insertion of the IL2RG gene near the LMO2 gene and thereby activating the LMO2 gene (a known oncogene). A third child developed leukemia...
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and Alain Fischer. Science 28 avril 2000 : Vol. 288. nº 5466, p. 669-672. LMO2-associated clonal T cell proliferation in two patients after gene therapy...
7 KB (707 words) - 08:41, 30 August 2024