• Thumbnail for Lanosterol
    Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast, plant steroids are produced...
    6 KB (303 words) - 14:35, 13 August 2024
  • Thumbnail for Steroid
    are manufactured in cells from the sterols lanosterol (opisthokonts) or cycloartenol (plants). Lanosterol and cycloartenol are derived from the cyclization...
    82 KB (8,473 words) - 23:42, 9 July 2024
  • Thumbnail for Lanosterol synthase
    cation and finally to lanosterol. Lanosterol is a key four-ringed intermediate in cholesterol biosynthesis. In humans, lanosterol synthase is encoded by...
    22 KB (2,582 words) - 17:29, 3 April 2024
  • Thumbnail for Lanosterol 14 alpha-demethylase
    Lanosterol 14α-demethylase (CYP51A1) is the animal version of a cytochrome P450 enzyme that is involved in the conversion of lanosterol to 4,4-dimethylcholesta-8(9)...
    10 KB (1,066 words) - 05:53, 15 December 2023
  • Thumbnail for Terbinafine
    the conversion of squalene to lanosterol. In fungi, lanosterol is then converted to ergosterol; in humans, lanosterol becomes cholesterol. However, as...
    20 KB (1,758 words) - 22:15, 3 August 2024
  • (vitamin E), dolichols, and squalene. Heme A has an isoprenoid tail, and lanosterol, the sterol precursor in animals, is derived from squalene and hence from...
    17 KB (1,703 words) - 16:36, 21 July 2024
  • intermediate in the synthesis of the cell membrane sterol precursors lanosterol and cycloartenol, as well as saponins. It is formed when squalene is oxidized...
    3 KB (97 words) - 06:26, 12 July 2024
  • Thumbnail for Sterol 14-demethylase
    14,24(28)-trien-3beta-ol, formate, NADP+, and H2O. Although the lanosterol 14α-demethylase is present in a wide variety of organisms, the enzyme...
    14 KB (1,517 words) - 11:47, 8 June 2024
  • Thumbnail for Prochloraz
    Similarly to other azole fungicides, prochloraz is an inhibitor of the enzyme lanosterol 14α-demethylase (CYP51A1), which is necessary for the production of ergosterol...
    6 KB (398 words) - 07:32, 26 November 2023
  • Thumbnail for Oxidosqualene cyclase
    cycloartenol Lanosterol synthase (LAS), found in all animals and fungi, and occasionally in plants, which produces primarily lanosterol Sterols and triterpenes...
    19 KB (2,196 words) - 19:46, 4 July 2024