MEG3 (maternally expressed 3) is a maternally expressed, imprinted long non-coding RNA gene. At least 12 different isoforms of MEG3 are generated by alternative...

also been implicated in Alzheimer's disease triggered by the production of MEG3 in the brain cells. In solid-organ transplantation, ischemia-reperfusion...

Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B. MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease...

cases even in complexes with small molecule modulators. For instance, lncRNA MEG3 was shown to regulate transcription factor p53 thanks to its compact structured...

targeting, they were able to manipulate two imprinted loci H19/IGF2 and DLK1/MEG3 to produce bi-maternal mice at high frequency and subsequently show that...

adipogenesis, or more simply the formation of fat cells. Imprinting (genetics) MEG3 - a gene occasionally expressed through polar overdominance Wermter, Anne-Kathrin;...

adenocarcinoma transcript 1 (MALAT1), H19, maternally expressed gene 3 (MEG3), prostate cancer antigen 3 (PCA3), the long intergenic non-coding RNA 00261...

arteries, has been associated with the hypermethylation of GNASAS, IL-10, MEG3, ABCA1, and the hypomethylation of INSIGF and IGF2. Additionally, upregulation...

modulate target gene expression with local and temporal precision. LncRNA Meg3 was found to control endothelial cell aging and its inhibition may serve...