Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter...
25 KB (2,592 words) - 14:02, 22 September 2024
Neurofilament light polypeptide, also known as neurofilament light chain, abbreviated to NF-L or Nfl and with the HGNC name NEFL is a member of the intermediate...
20 KB (2,166 words) - 00:24, 24 September 2024
copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The...
8 KB (974 words) - 19:59, 26 July 2022
Cerebral atrophy (section Neurofilament light chain)
of biomarkers, namely one called neurofilament light chain (NFL), in patients with Alzheimer's disease. Neurofilament light chain is a protein that is...
21 KB (2,189 words) - 18:00, 14 October 2024
Neurofilament, heavy polypeptide (NEFH) is a protein that in humans is encoded by the NEFH gene. It is the gene for a heavy protein subunit that is combined...
1 KB (155 words) - 01:53, 21 August 2023
on degeneration. Another class of antibody to neurofilament NF-L was shown to bind only neurofilaments in healthy neurons and their processes but failed...
11 KB (1,103 words) - 17:06, 13 September 2024
antibody to MAP2 (green), Neurofilament NF-H (red) and DNA (blue). MAP2 is found in neuronal dendrites, while the neurofilament is found predominantly in...
3 KB (278 words) - 05:48, 27 December 2023
PMID 9846894 – via EuropeMC. M, Sjögren; E, Englund (2004). "Negative neurofilament light and tau immunostaining in frontotemporal dementia". Dementia and...
16 KB (1,497 words) - 17:20, 22 October 2024
Neurofilament medium polypeptide (NF-M) is a protein that in humans is encoded by the NEFM gene. Neurofilaments are type IV intermediate filament heteropolymers...
7 KB (968 words) - 04:31, 30 January 2023
neuroimaging afterwards. Further, levels of the neuroaxonal damage biomarker neurofilament light chain are elevated in blood plasma after TAVI. Whereas clinical...
31 KB (3,425 words) - 04:05, 10 May 2024