Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter...

Neurofilament light polypeptide, also known as neurofilament light chain, abbreviated to NF-L or Nfl and with the HGNC name NEFL is a member of the intermediate...

copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The...

of biomarkers, namely one called neurofilament light chain (NFL), in patients with Alzheimer's disease. Neurofilament light chain is a protein that is...

Neurofilament, heavy polypeptide (NEFH) is a protein that in humans is encoded by the NEFH gene. It is the gene for a heavy protein subunit that is combined...

on degeneration. Another class of antibody to neurofilament NF-L was shown to bind only neurofilaments in healthy neurons and their processes but failed...

antibody to MAP2 (green), Neurofilament NF-H (red) and DNA (blue). MAP2 is found in neuronal dendrites, while the neurofilament is found predominantly in...

PMID 9846894 – via EuropeMC. M, Sjögren; E, Englund (2004). "Negative neurofilament light and tau immunostaining in frontotemporal dementia". Dementia and...

Neurofilament medium polypeptide (NF-M) is a protein that in humans is encoded by the NEFM gene. Neurofilaments are type IV intermediate filament heteropolymers...

neuroimaging afterwards. Further, levels of the neuroaxonal damage biomarker neurofilament light chain are elevated in blood plasma after TAVI. Whereas clinical...