Phosphodiesterase 1, PDE1, EC 3.1.4.1, systematic name oligonucleotide 5′-nucleotidohydrolase) is a phosphodiesterase enzyme also known as calcium- and...
22 KB (2,564 words) - 01:35, 14 June 2024
also inhibit PDE1 more than tadalafil. PDE1 is found in the brain, heart, and vascular smooth muscle. It is thought that the inhibition of PDE1 by sildenafil...
36 KB (3,239 words) - 12:12, 6 August 2024
3). The superfamily of PDE enzymes is classified into 11 families, namely PDE1-PDE11, in mammals. The classification is based on: amino acid sequences substrate...
15 KB (1,725 words) - 08:12, 7 August 2024
v t e Phosphodiesterase inhibitors PDE1 MMPX SCH-51866 Vinpocetine PDE2 BAY 60-7550 Carbazeran EHNA Oxindole PDP PDE3 Adibendan Amrinone (inamrinone) Anagrelide...
200 KB (19,870 words) - 14:51, 7 August 2024
by hydrolyzing cGMP into 5'-GMP. PDE 5, -6 and -9 are cGMP-specific while PDE1, -2, -3, -10 and -11 can hydrolyse both cAMP and cGMP. Phosphodiesterase...
11 KB (1,122 words) - 01:24, 20 February 2024
v t e Phosphodiesterase inhibitors PDE1 MMPX SCH-51866 Vinpocetine PDE2 BAY 60-7550 Carbazeran EHNA Oxindole PDP PDE3 Adibendan Amrinone (inamrinone) Anagrelide...
18 KB (1,886 words) - 15:58, 11 November 2023
PDE5 than on other known phosphodiesterases (10-fold for PDE6, >80-fold for PDE1, >700-fold for PDE2, PDE3, PDE4, PDE7, PDE8, PDE9, PDE10, and PDE11). The...
16 KB (1,849 words) - 14:58, 23 May 2024
v t e Phosphodiesterase inhibitors PDE1 MMPX SCH-51866 Vinpocetine PDE2 BAY 60-7550 Carbazeran EHNA Oxindole PDP PDE3 Adibendan Amrinone (inamrinone) Anagrelide...
19 KB (1,818 words) - 06:09, 19 May 2024
v t e Phosphodiesterase inhibitors PDE1 MMPX SCH-51866 Vinpocetine PDE2 BAY 60-7550 Carbazeran EHNA Oxindole PDP PDE3 Adibendan Amrinone (inamrinone) Anagrelide...
21 KB (1,838 words) - 00:10, 22 July 2024
v t e Phosphodiesterase inhibitors PDE1 MMPX SCH-51866 Vinpocetine PDE2 BAY 60-7550 Carbazeran EHNA Oxindole PDP PDE3 Adibendan Amrinone (inamrinone) Anagrelide...
14 KB (1,266 words) - 17:48, 27 July 2024