• Thumbnail for PIK3R1
    regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of...
    28 KB (3,136 words) - 20:06, 8 April 2024
  • Thumbnail for SHORT syndrome
    characteristics and molecular genetic testing that will show a mutation on gene PIK3R1 (5q13.1), which codifies the regulating alpha subunit of phosphatidylinositol...
    6 KB (485 words) - 21:43, 24 February 2024
  • Thumbnail for Leniolisib
    delta syndrome is caused by mutations in either of two genes, PIK3CD or PIK3R1, that regulate the maturation of white blood cells, especially B cells and...
    9 KB (583 words) - 17:26, 7 February 2024
  • Thumbnail for Endometrial cancer
    unknown FGFR2 point mutation 16% unknown KRAS point mutation 10–20% unknown PIK3R1 point mutation 43% unknown TP53 point mutation 10–20% 90% PTEN point mutation...
    105 KB (10,821 words) - 02:34, 12 July 2024
  • Thumbnail for Phosphoinositide 3-kinase
    first three regulatory subunits are all splice variants of the same gene (Pik3r1), the other two being expressed by other genes (Pik3r2 and Pik3r3, p85β...
    32 KB (3,463 words) - 17:34, 20 November 2023
  • Thumbnail for SH2 domain
    GRB7 HCK; HSH2D INPP5D; INPPL1; ITK; JAK2; LCK; LCP2; LYN MATK; NCK1; NCK2 PIK3R1; PIK3R2; PIK3R3; PLCG1; PLCG2; PTK6; PTPN11; PTPN6; RASA1 SH2B1; SH2B2;...
    13 KB (1,341 words) - 04:09, 6 March 2024
  • Thumbnail for KIT (gene)
    CD81, CD9, CRK, CRKL, DOK1, FES, GRB10, Grb2, KITLG, LNK, LYN, MATK, MPDZ, PIK3R1, PTPN11, PTPN6, STAT1, SOCS1, SOCS6, SRC, and TEC. Cytokine receptor List...
    35 KB (4,117 words) - 14:30, 7 July 2024
  • O00329 12160 PIK3CG HGNC:8978 P48736 12161 PIK3IP1 HGNC:24942 Q96FE7 12162 PIK3R1 HGNC:8979 P27986 12163 PIK3R2 HGNC:8980 O00459 12164 PIK3R3 HGNC:8981 Q92569...
    282 KB (17 words) - 07:55, 20 June 2024
  • Thumbnail for Janus kinase 2
    shown to interact with: DNAJA3 EGFR EPOR FYN Grb2 GHR IRS1 IL12RB2 IL5RA PIK3R1 PPP2R4 PTK2 PTPN11 PTPN6 PRMT5 SH2B1 SHC1 SOCS3 STAT5A STAT5B STAM SOCS1...
    28 KB (3,166 words) - 14:44, 22 June 2024
  • Thumbnail for CD28
    homodimerization. CD28 has been shown to interact with: GRAP2, Grb2, and PIK3R1. List of human clusters of differentiation GRCh38: Ensembl release 89: ENSG00000178562...
    27 KB (3,419 words) - 16:44, 7 May 2024