• Thumbnail for Proliferating cell nuclear antigen
    Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for...
    53 KB (6,158 words) - 18:54, 23 April 2024
  • Thumbnail for Eukaryotic DNA replication
    polymerase α, DNA polymerase ε, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA) onto chromatin. Within a Xenopus nucleus-free system...
    119 KB (14,646 words) - 22:02, 3 July 2024
  • Thumbnail for Ki-67 (protein)
    Ki-67 (protein) has been shown to interact with CBX3. PCNA - Proliferating Cell Nuclear Antigen, expressed during the DNA synthesis. Immunofluorescent antibody...
    10 KB (1,365 words) - 02:06, 17 June 2024
  • Thumbnail for AOH1996
    anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as...
    6 KB (572 words) - 19:06, 29 May 2024
  • Thumbnail for DNA clamp
    from a specific subunit of DNA polymerase delta called the proliferating cell nuclear antigen (PCNA). The N-terminal and C-terminal domains of PCNA are...
    23 KB (2,044 words) - 07:04, 10 March 2024
  • Thumbnail for P21
    P21 (category Cell cycle regulators)
    activity via ubiquitin ligase activity. p21 interacts with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory...
    34 KB (3,978 words) - 08:00, 23 February 2024
  • Thumbnail for DNA mismatch repair
    for RFC-dependent loading of the replication sliding clamp, proliferating cell nuclear antigen (PCNA), in an orientation-specific manner, such that one face...
    35 KB (4,179 words) - 12:12, 19 July 2024
  • Thumbnail for Antinuclear antibody
    bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins...
    54 KB (6,097 words) - 21:43, 28 June 2024
  • Thumbnail for Okazaki fragments
    failures could be lethal to the cell. Further research implicates the supplementary role of proliferating cell nuclear antigen (PCNA) to DNA ligase I's function...
    33 KB (4,435 words) - 14:24, 7 June 2024
  • exhibits increased processivity when interacting with the proliferating cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor...
    2 KB (259 words) - 21:21, 11 December 2023