Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for...
53 KB (6,158 words) - 18:54, 23 April 2024
polymerase α, DNA polymerase ε, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA) onto chromatin. Within a Xenopus nucleus-free system...
119 KB (14,646 words) - 22:02, 3 July 2024
Ki-67 (protein) (redirect from Ki-67 antigen)
Ki-67 (protein) has been shown to interact with CBX3. PCNA - Proliferating Cell Nuclear Antigen, expressed during the DNA synthesis. Immunofluorescent antibody...
10 KB (1,365 words) - 02:06, 17 June 2024
anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as...
6 KB (572 words) - 19:06, 29 May 2024
from a specific subunit of DNA polymerase delta called the proliferating cell nuclear antigen (PCNA). The N-terminal and C-terminal domains of PCNA are...
23 KB (2,044 words) - 07:04, 10 March 2024
P21 (category Cell cycle regulators)
activity via ubiquitin ligase activity. p21 interacts with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory...
34 KB (3,978 words) - 08:00, 23 February 2024
for RFC-dependent loading of the replication sliding clamp, proliferating cell nuclear antigen (PCNA), in an orientation-specific manner, such that one face...
35 KB (4,179 words) - 12:12, 19 July 2024
Antinuclear antibody (redirect from Anti-nuclear antibody)
bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins...
54 KB (6,097 words) - 21:43, 28 June 2024
failures could be lethal to the cell. Further research implicates the supplementary role of proliferating cell nuclear antigen (PCNA) to DNA ligase I's function...
33 KB (4,435 words) - 14:24, 7 June 2024
exhibits increased processivity when interacting with the proliferating cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor...
2 KB (259 words) - 21:21, 11 December 2023