Purine analogues are antimetabolites that mimic the structure of metabolic purines. Nucleobase analogues Thiopurines such as thioguanine are used to treat...

include: folic acid analogues, such as methotrexate purine analogues, such as azathioprine and mercaptopurine pyrimidine analogues, such as fluorouracil...

blood clots, lymphopenia, hepatotoxicity and infections. Azathioprine Purine analogue that inhibits lymphocyte proliferation via conversion to mercaptopurine...

the fluorescent 2-amino-6-(2-thienyl)purine and pyrrole-2-carbaldehyde. In medicine, several nucleoside analogues are used as anticancer and antiviral...

pregnancy may result in harm to the baby. Azathioprine belongs to the purine analogues subclass of antimetabolites family of medications. It works via 6-thioguanine...

active forms of relapsing-remitting multiple sclerosis. Cladribine is a purine analogue that selectively targets and suppresses lymphocytes implicated in the...

archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms...

chemists who were working at the Burroughs Wellcome Co. in Tuckahoe, many purine analogues were tested, culminating in the discovery of 6-mercaptopurine (6-MP)...

Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular...

injury. Xanthine oxidase inhibitors are of two kinds: purine analogues and others. Purine analogues include allopurinol, oxypurinol, and tisopurine. Others...