• Thumbnail for RAB27A
    Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene. The protein encoded by this gene belongs to the small GTPase superfamily...
    13 KB (1,563 words) - 11:44, 14 January 2024
  • Thumbnail for Griscelli syndrome
    seen in Rab27A deficient children, this is thought to be a secondary effect of the immune problems, and not directly due to the lack of Rab27A. Munc13-4...
    9 KB (980 words) - 23:20, 7 September 2024
  • Thumbnail for Choroideremia
    retina. RAB27A, a Rab that has essential functions in the retina, has been shown to be preferentially prenylated by REP1. Additionally, the Rab27a-REP1 and...
    28 KB (3,087 words) - 00:22, 15 August 2024
  • Thumbnail for Melanophilin
    The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein...
    10 KB (1,308 words) - 21:37, 27 March 2024
  • Thumbnail for Hemophagocytic lymphohistiocytosis
    virus. These mutations include those in the following genes: UNC13D, STX11, RAB27A, STXBP2, LYST, PRF1 1, SH2D1A, BIRC4, ITK, CD27, and MAGT1. Secondary HLH...
    29 KB (3,295 words) - 15:00, 22 September 2024
  • Thumbnail for Unconventional myosin-Va
    neurons and melanocytes. MYO5A has been shown to interact with DYNLL1, RAB27A, DYNLL2, RPGRIP1L, and Rab3A. Defects in Myosin Va are associated with Griscelli...
    15 KB (1,884 words) - 02:39, 22 July 2024
  • Thumbnail for UNC13D
    PMID 19131769. S2CID 25882775. Saxena SK, Horiuchi H, Fukuda M (2006). "Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like...
    8 KB (974 words) - 15:32, 7 March 2024
  • Thumbnail for EXPH5
    known as EXPH5, is a human gene. EXPH5 has been shown to interact with RAB27A. GRCh38: Ensembl release 89: ENSG00000110723 – Ensembl, May 2017 GRCm38:...
    3 KB (383 words) - 00:27, 4 March 2023
  • Thumbnail for SYTL1
    humans is encoded by the SYTL1 gene. SYTL1 has been shown to interact with RAB27A. GRCh38: Ensembl release 89: ENSG00000142765 – Ensembl, May 2017 GRCm38:...
    5 KB (555 words) - 08:07, 7 January 2024
  • Thumbnail for SYTL2
    to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A), which suggests a role in vesicle trafficking. Multiple alternatively spiced...
    9 KB (1,265 words) - 00:52, 4 March 2023