Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a...
29 KB (3,631 words) - 22:34, 11 April 2024
Aorta-gonad-mesonephros (section Runx1)
their expression of Ly6A-GFP (Sca1), CD31, CD34, cKit, CD27, CD41, Gata2, Runx1, Notch1, and BMP amongst others. The aorta-gonad-mesonephros (AGM) region...
24 KB (3,012 words) - 04:30, 5 February 2024
neoplasms with germline DDX41 mutation Myeloid neoplasms with germline RUNX1 mutation Myeloid neoplasms with germline ANKRD26 mutation Myeloid neoplasms...
24 KB (2,329 words) - 06:57, 14 July 2024
specific abnormality in childhood B-ALL is the t(12;21) ETV6–RUNX1 translocation, in which the RUNX1 gene, encoding a protein involved in transcriptional control...
77 KB (7,766 words) - 03:16, 21 July 2024
ABL; 22 BCR) Acute myeloblastic leukemia with maturation t(8 RUNX1T1;21 RUNX1) Acute promyelocytic leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia...
149 KB (14,922 words) - 13:09, 4 August 2024
acute myeloid leukemia is the formation of a fusion protein, AML1-ETO or RUNX1-RUNX1T1, due to a translocation of chromosome 8 to chromosome 21 or t(8;21)...
25 KB (3,160 words) - 20:16, 30 November 2023
ABL; 22 BCR) Acute myeloblastic leukemia with maturation t(8 RUNX1T1;21 RUNX1) Acute promyelocytic leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia...
77 KB (9,067 words) - 17:47, 1 August 2024
mutation is found in 10% of cases. Mutations in transcription factors such as RUNX1, CEBPA, NPM1 and WT1 have been found in up to 30% of cases. Mutations of...
25 KB (2,922 words) - 14:19, 29 August 2023
processing 1 homolog B RSPH1: encoding protein radial spoke head 1 homolog RUNX1: encoding protein Runt-related transcription factor 1 RWDD2B: encoding protein...
34 KB (3,087 words) - 13:30, 30 July 2024
c-KIT pharmacologically. It is expected that additional markers (e.g., RUNX1, ASXL1, and TP53) that have consistently been associated with an inferior...
75 KB (7,429 words) - 11:09, 28 July 2024