Rasagiline, sold under the brand name Azilect among others, is a medication which is used in the treatment of Parkinson's disease. It is used as a monotherapy...
90 KB (8,916 words) - 04:53, 12 November 2024
MAO-B inhibitor and antiparkinsonian agent rasagiline ((R)-N-propargyl-1-aminoindan). In contrast to rasagiline, it lacks significant monoamine oxidase inhibition...
9 KB (692 words) - 03:15, 12 November 2024
pharmacologically active and is an active metabolite of the antiparkinsonian agent rasagiline. Through its (R)-enantiomer (R)-1-aminoindane, 1-aminoindane has pharmacological...
10 KB (739 words) - 05:54, 14 September 2024
is less selective for MAO-B inhibition than AGN-1135 (racemic rasagiline) or rasagiline. In addition to its MAOI activity, SU-11739 has been reported...
7 KB (534 words) - 07:05, 1 October 2024
imipramine, desipramine), monoamine oxidase inhibitors (MAOIs) (e.g., rasagiline), serotonin antagonists and reuptake inhibitors (SARIs) (e.g., nefazodone)...
4 KB (360 words) - 02:54, 18 December 2022
more potent than D-deprenyl. AGN-1135 (racemic rasagiline) SU-11739 (racemic N-methylated rasagiline) Parnham, M. J. (1993). "The History of l-Deprenyl"...
7 KB (517 words) - 21:14, 17 October 2024
racemic rasagiline or as N-propargyl-1-aminoindane) is a monoamine oxidase inhibitor (MAOI) that was never marketed. It is the racemic form of rasagiline and...
4 KB (212 words) - 02:30, 15 September 2024
Management of Parkinson's disease (section Rasagiline)
B propargyl amine inhibitor rasagiline (N-propargyl-1-R-aminoindan, Azilect((R))). The oral bioavailability of rasagiline is 35%, it reaches T(max) after...
71 KB (8,447 words) - 17:36, 19 February 2024
Antagonists of MAEs, like EPPTB (a known TAAR1 antagonist), 3-F-BPAP, and rasagiline, have been identified. A few endogenous MAEs have been identified, including...
57 KB (5,873 words) - 01:10, 30 October 2024
Parkinson's disease. It was developed from structural modification of rasagiline. The drug acts as a reversible acetylcholinesterase and butyrylcholinesterase...
6 KB (523 words) - 22:17, 17 August 2024