• Thumbnail for Rasagiline
    Rasagiline, sold under the brand name Azilect among others, is a medication which is used in the treatment of Parkinson's disease. It is used as a monotherapy...
    90 KB (8,916 words) - 04:53, 12 November 2024
  • Thumbnail for (R)-1-Aminoindan
    MAO-B inhibitor and antiparkinsonian agent rasagiline ((R)-N-propargyl-1-aminoindan). In contrast to rasagiline, it lacks significant monoamine oxidase inhibition...
    9 KB (692 words) - 03:15, 12 November 2024
  • Thumbnail for 1-Aminoindane
    pharmacologically active and is an active metabolite of the antiparkinsonian agent rasagiline. Through its (R)-enantiomer (R)-1-aminoindane, 1-aminoindane has pharmacological...
    10 KB (739 words) - 05:54, 14 September 2024
  • Thumbnail for SU-11739
    is less selective for MAO-B inhibition than AGN-1135 (racemic rasagiline) or rasagiline. In addition to its MAOI activity, SU-11739 has been reported...
    7 KB (534 words) - 07:05, 1 October 2024
  • imipramine, desipramine), monoamine oxidase inhibitors (MAOIs) (e.g., rasagiline), serotonin antagonists and reuptake inhibitors (SARIs) (e.g., nefazodone)...
    4 KB (360 words) - 02:54, 18 December 2022
  • Thumbnail for Deprenyl
    more potent than D-deprenyl. AGN-1135 (racemic rasagiline) SU-11739 (racemic N-methylated rasagiline) Parnham, M. J. (1993). "The History of l-Deprenyl"...
    7 KB (517 words) - 21:14, 17 October 2024
  • Thumbnail for AGN-1135
    racemic rasagiline or as N-propargyl-1-aminoindane) is a monoamine oxidase inhibitor (MAOI) that was never marketed. It is the racemic form of rasagiline and...
    4 KB (212 words) - 02:30, 15 September 2024
  • B propargyl amine inhibitor rasagiline (N-propargyl-1-R-aminoindan, Azilect((R))). The oral bioavailability of rasagiline is 35%, it reaches T(max) after...
    71 KB (8,447 words) - 17:36, 19 February 2024
  • Thumbnail for Monoaminergic activity enhancer
    Antagonists of MAEs, like EPPTB (a known TAAR1 antagonist), 3-F-BPAP, and rasagiline, have been identified. A few endogenous MAEs have been identified, including...
    57 KB (5,873 words) - 01:10, 30 October 2024
  • Thumbnail for Ladostigil
    Parkinson's disease. It was developed from structural modification of rasagiline. The drug acts as a reversible acetylcholinesterase and butyrylcholinesterase...
    6 KB (523 words) - 22:17, 17 August 2024