• Thumbnail for Sodium/glucose cotransporter 1
    Sodium/glucose cotransporter 1 (SGLT1) also known as solute carrier family 5 member 1 is a protein in humans that is encoded by the SLC5A1 gene which...
    17 KB (1,986 words) - 22:15, 3 December 2023
  • mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose...
    10 KB (969 words) - 18:19, 22 September 2024
  • transport proteins in the nephron (the functional units of the kidney), unlike SGLT1 inhibitors that perform a similar function in the intestinal mucosa. The...
    44 KB (4,559 words) - 22:03, 7 July 2024
  • Thumbnail for Oral rehydration therapy
    (enterocytes). Sodium passes into these cells by co-transport with glucose, via the SGLT1 protein. From the intestinal epithelial cells, sodium is pumped by active...
    48 KB (5,300 words) - 11:29, 19 August 2024
  • cotransport systems. The first of these membrane transport proteins was named SGLT1 followed by the discovery of SGLT2. Robert Krane also played a prominent...
    31 KB (3,826 words) - 04:03, 30 September 2024
  • Thumbnail for Sodium/glucose cotransporter 2
    the remaining glucose absorption is by sodium/glucose cotransporter 1 (SGLT1) in more distal sections of the proximal tubule. SGLT2 inhibitors are also...
    8 KB (853 words) - 17:51, 22 September 2024
  • Thumbnail for Cotransporter
    Na+/glucose cotransporter (SGLT1) – is also known as sodium-glucose cotransporter 1 and is encoded by the SLC5A1 gene. SGLT1 is an electrogenic transporter...
    22 KB (2,288 words) - 20:18, 2 October 2023
  • Thumbnail for Mizagliflozin
    Mizagliflozin is an SGLT1 inhibitor developed as a potential treatment for chronic constipation. It progressed as far as Phase II trials in humans but...
    4 KB (238 words) - 12:30, 20 September 2024
  • Thumbnail for Diarrhea
    transporters targeted by enteric infections Function   Transporter Absorption NHE, SGLT1, ENaC, DRA Secretion CaCC, NKCC1, CFTR Absorption and secretion Sodium potassium...
    86 KB (9,223 words) - 00:43, 25 September 2024
  • Thumbnail for Glucose transporter
    idea has turned into one of the most studied of all transporter proteins (SGLT1), the sodium–glucose cotransporter. Glucose+Transport+Proteins,+Facilitative...
    16 KB (1,327 words) - 13:39, 23 August 2024