transporter), member 12, also known as SLC22A12 and URAT1, is a protein which in humans is encoded by the SLC22A12 gene. The protein encoded by this gene...
9 KB (1,079 words) - 11:05, 18 July 2024
contributing to about 60% of variability in uric acid level. The SLC2A9, SLC22A12, and ABCG2 genes have been found to be commonly associated with gout and...
83 KB (8,330 words) - 07:19, 21 August 2024
Losartan is a uricosuric. As a specific inhibitor of the urate transporter 1 (SLC22A12, URAT1), losartan blocks the uptake of uric acid into cells, thus leaving...
41 KB (3,260 words) - 09:46, 16 August 2024
reabsorption inhibitor that has uric acid lowering activity by inhibiting URAT1/SLC22A12 receptor. It is a structural analog of Benzbromarone. Kuriyama S (March...
5 KB (251 words) - 15:30, 1 February 2024
urate, have so far been identified: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1. GLUT9, encoded by the SLC2A9 gene,...
37 KB (3,698 words) - 02:33, 5 August 2024
SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A19 SLC22A20...
31 KB (3,578 words) - 01:13, 8 August 2024
act in vitro by blocking the function of a protein encoded by the gene SLC22A12, also known as urate transporter 1 or URAT1. URAT1 is the central mediator...
7 KB (843 words) - 15:24, 1 November 2023
SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A19 SLC22A20...
25 KB (2,937 words) - 17:58, 15 January 2024
T, Hosoya T (September 2008). "Age and origin of the G774A mutation in SLC22A12 causing renal hypouricemia in Japanese". Clin. Genet. 74 (3): 243–51. doi:10...
13 KB (1,438 words) - 04:56, 14 August 2024
SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A19 SLC22A20...
17 KB (2,097 words) - 19:08, 13 July 2024