SLX4 (also known as BTBD12 and FANCP) is a protein involved in DNA repair, where it has important roles in the final steps of homologous recombination...
4 KB (474 words) - 11:31, 7 February 2024
study suggests that a scaffold protein called SLX4 may participate in this regulation. Specifically, SLX4 knockout mice largely phenocopies the MUS81 knockout—once...
32 KB (3,709 words) - 00:41, 26 June 2024
SLX4 interacting protein is a protein that in humans is encoded by the SLX4IP gene. SLX4 interacting protein (SLX4IP) exists in a monomeric form, and interacts...
12 KB (1,360 words) - 20:19, 22 January 2024
FANCI, FANCJ (BRIP1), FANCL, FANCM, FANCN (PALB2), FANCO (RAD51C), FANCP (SLX4), FANCQ (XPF), FANCS (BRCA1), FANCT (UBE2T), FANCU (XRCC2), FANCV (REV7)...
37 KB (4,140 words) - 08:44, 11 April 2024
P0DP57 15266 SLX1A HGNC:20922 Q9BQ83 15267 SLX1B HGNC:28748 Q9BQ83 15268 SLX4 HGNC:23845 Q8IY92 15269 SLX4IP HGNC:16225 Q5VYV7 15270 SLX9 HGNC:15811 Q9NSI2...
242 KB (17 words) - 23:17, 27 April 2024
MiDAS essential scaffolding protein SLX4, which forms a large nuclease complex. The proposed mechanisms for TOPBP1/SLX4 mediated MiDAS are either replication...
33 KB (3,675 words) - 22:00, 23 December 2023
It is this complex that recruits FAN1 as well as other nucleases such as SLX4. Ubiquinated FANCD2 interacts with the FAN1 nuclease. Upon its recruitment...
16 KB (1,817 words) - 20:16, 22 January 2024
nucleases, known as Rad1/Rad10, which are brought to the flaps by the Saw1 and Slx4 proteins. New DNA synthesis fills in any gaps, and ligation restores the...
106 KB (12,105 words) - 20:29, 9 March 2024
discoveries of genes implicated in disease, including finding: Mutation of SLX4 causes a new type of Fanconi anemia. Nine new genes that influence bone strength...
7 KB (810 words) - 18:59, 6 June 2024
member 9 SLC2A4RG: encoding protein SLC2A4 regulator SLX4IP: encoding protein SLX4 interacting protein SNPH: encoding protein Syntaphilin SPATA2: encoding protein...
22 KB (1,573 words) - 04:43, 27 December 2023