A spliceosome is a large ribonucleoprotein (RNP) complex found primarily within the nucleus of eukaryotic cells. The spliceosome is assembled from small...

rearrangement, complex C is formed, and the spliceosome is active for catalysis. In the catalytically active spliceosome U2 and U6 snRNAs fold to form a conserved...

The minor spliceosome is a ribonucleoprotein complex that catalyses the removal (splicing) of an atypical class of spliceosomal introns (U12-type) from...

splicing occurs in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs). There exist...

conserved, and unique protein that resides in the catalytic core of the spliceosome and has been found to have a central role in molecular rearrangements...

identified: Introns in nuclear protein-coding genes that are removed by spliceosomes (spliceosomal introns) Introns in nuclear and archaeal transfer RNA genes...

together to form the mature mRNA. Splicing is conducted by the spliceosome. The spliceosome is a large ribonucleoprotein which cleaves the RNA at the splicing...

splice site and are dependent on SON to ensure efficient splicing and spliceosome recognition. The SON gene also plays a critical role during development...

in the human gene RNU4-2, which encodes an RNA component of the major spliceosome. It is characterized by hypotonia, global developmental delay, severely...

transcription, the capping of the RNA transcript, and attachment to the spliceosome for RNA splicing. The CTD typically consists of up to 52 repeats (in...