Spo11 is a protein that in humans is encoded by the SPO11 gene. Spo11, in a complex with mTopVIB, creates double strand breaks to initiate meiotic recombination...

present in the genome. One gene, Spo11, was absent in the Mycetozoa, raising questions about the assumed universal role of Spo11 as an initiator of meiosis...

the loops emanate. Recombination is initiated in this stage by the enzyme SPO11 which creates programmed double strand breaks (around 300 per meiosis in...

of the Miami Heat Sankt Peter-Ording, a tourist town in northern Germany Spo11, a protein used in a complex along with Mre11 and Rad50 during meiotic recombination...

evolutionary advantage. Chromosomal crossover often begins when a protein called Spo11 makes a targeted double-strand break in DNA. These sites are non-randomly...

are introduced into the DNA by exposure to DNA damaging agents, or the Spo11 protein. One or more exonucleases then digest the 5' ends generated by the...

process is evidenced to be caused in a large part by the highly conserved Spo11 protein through a mechanism similar to that seen with topoisomerase in DNA...

recently been identified in the Acanthamoeba genome. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh and Mlh. This finding suggests...

introduction of DSBs in DNA often employs the topoisomerase-like protein SPO11. CO recombination may also be initiated by external sources of DNA damage...

Identification of the meiotic toolkit in diatoms and exploration of meiosis-specific SPO11 and RAD51 homologs in the sexual species Pseudo-nitzschia multistriata and...