• Thumbnail for Sulfanilamide
    Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized...
    13 KB (1,122 words) - 15:36, 8 October 2024
  • Thumbnail for Elixir sulfanilamide
    Elixir sulfanilamide was an improperly prepared sulfonamide antibiotic that caused mass poisoning in the United States in 1937. It is believed to have...
    6 KB (692 words) - 00:35, 24 March 2024
  • Thumbnail for Sulfonamide (medicine)
    the inactive dye portion a smaller, colorless, active compound called sulfanilamide. The discovery helped establish the concept of "bioactivation" and dashed...
    18 KB (1,857 words) - 10:47, 27 September 2024
  • Thumbnail for Prontosil
    became the first oral version of sulfanilamide by Bayer, which had actually obtained a German patent on sulfanilamide as early as 1909, without realizing...
    15 KB (1,603 words) - 13:27, 2 November 2024
  • the elixir sulfanilamide disaster of 1937, described as one of the most consequential mass poisonings of the 20th century. Elixir sulfanilamide was formulated...
    3 KB (330 words) - 18:37, 4 October 2023
  • Thumbnail for Nazi human experimentation
    medical experiments revolving around food, seawater, epidemic jaundice, sulfanilamide, blood coagulation and phlegmon. According to the indictments at the...
    51 KB (5,686 words) - 09:08, 9 October 2024
  • Neosalvarsan 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide 1936 – Sulfanilamide 1938 – Sulfapyridine (M&B 693) 1939 – sulfacetamide...
    6 KB (508 words) - 13:47, 2 March 2024
  • Thumbnail for Federal Food, Drug, and Cosmetic Act of 1938
    influenced by the death of more than 100 patients due to elixir sulfanilamide, a sulfanilamide medication where the toxic solvent diethylene glycol was used...
    33 KB (3,332 words) - 02:54, 27 August 2024
  • Thumbnail for Medication
    regulation of drug development and drug sales. In the U.S., the Elixir Sulfanilamide disaster led to the establishment of the Food and Drug Administration...
    69 KB (7,416 words) - 16:21, 10 November 2024
  • Thumbnail for Sulfonamide
    sometimes used as a synonym for sulfa drug, a derivative or variation of sulfanilamide. The first sulfonamide was discovered in Germany in 1932. Sulfonamides...
    8 KB (847 words) - 18:55, 12 March 2024