TAP-associated glycoprotein, also known as tapasin or TAPBP, is a protein that in humans is encoded by the TAPBP gene. The TAPBP gene encodes a transmembrane...
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multimeric complex called the Peptide loading complex consisting of TAP, tapasin, calreticulin, calnexin, and Erp57 (PDIA3). Calnexin acts to stabilize...
21 KB (2,610 words) - 08:24, 9 August 2024
Peptide loading complex (section Tapasin)
TAP), the oxidoreductase ERp57, the MHC-I heterodimer, and the chaperones tapasin and calreticulin. TAP transports proteasomal degradation products from...
12 KB (1,550 words) - 08:08, 28 June 2024
calreticulin chaperone protein, TAP (with a bound peptide fragment), and tapasin. Tapasin increases the stability of TAP, in addition to stabilizing the entire...
27 KB (3,411 words) - 01:57, 10 March 2024
calreticulin, Erp57, protein disulfide isomerase (PDI), and tapasin. Specifically, the complex of TAP, tapasin, MHS Class 1, ERp57, and calreticulin is called the...
14 KB (1,672 words) - 15:05, 12 October 2024
of its time are in bold): Kun minä eilen illalla palasin labbiksesta, tapasin Aasiksen kohdalla Supiksen, ja niin me laskeusimme tänne Espikselle, jossa...
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that are under clinical investigation for treating chronic hepatitis B. Tapasin can interact with HBcAg18-27 and enhance cytotoxic T-lymphocyte response...
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presentation, as well as (2) molecules aiding antigen-processing (such as TAP and tapasin). One chain, called α, whose ligands are the CD8 receptor—borne notably...
58 KB (6,785 words) - 20:25, 21 September 2024
The partially folded MHC class I molecule then interacts with TAP via tapasin (the complete complex also contains calreticulin and Erp57 and, in mice...
12 KB (1,763 words) - 18:48, 6 April 2023
for example in transporter associated with antigen processing (TAP) or tapasin. On the other hand, a complete loss of MHC I is a trigger for NK cells...
33 KB (3,766 words) - 14:14, 19 June 2024