• Thumbnail for Tolcapone
    Tolcapone, sold under the brand name Tasmar, is a medication used to treat Parkinson's disease (PD). It is a selective, potent and reversible nitrocatechol-type...
    25 KB (2,605 words) - 15:30, 6 August 2024
  • Thumbnail for Catechol-O-methyltransferase inhibitor
    Marketed Entacapone (Comtan, Comtess, Stalevo) Opicapone (Ongentys) Tolcapone (Tasmar) Not marketed Nebicapone (BIA 3-202) Nitecapone (OR-462) Entacapone...
    10 KB (1,109 words) - 07:30, 2 September 2024
  • Thumbnail for Dopaminergic
    opicapone, and tolcapone, which are used in the treatment of Parkinson's disease. Entacapone and opicapone are peripherally selective, but tolcapone significantly...
    23 KB (2,278 words) - 09:55, 28 September 2024
  • Thumbnail for Catechol-O-methyltransferase
    and tolcapone ... have been demonstrated to reduce the dose of L-DOPA required and also cause improvement in clinical symptoms, although tolcapone emerged...
    29 KB (3,236 words) - 00:14, 10 July 2024
  • tolcapone "orphan drug status" in studies aiming at the treatment of transthyretin familial amyloidosis (ATTR). However, as of 2015[update] tolcapone...
    10 KB (1,240 words) - 00:53, 29 November 2023
  • Tiagabine Tianeptine Tiapride Thioproperazine Thioridazine Thiothixene Tolcapone Topiramate Tranylcypromine Trazodone Triclofos Trifluoperazine Trifluperidol...
    26 KB (1,722 words) - 21:40, 3 October 2024
  • the CNS penetrant specific catecholamine-O-methyltransferase inhibitor Tolcapone. Furthermore, episodic memory is enhanced through AZD3480, a selective...
    37 KB (4,565 words) - 12:11, 30 August 2024
  • Centrally active catechol-O-methyltransferase inhibitors (COMTIs) like tolcapone, which are likewise dopaminergic agents, have been studied in the treatment...
    58 KB (6,077 words) - 22:26, 28 September 2024
  • Thumbnail for Catecholamine
    of the sympathetic nervous system.[citation needed] Some drugs, like tolcapone (a central COMT-inhibitor), raise the levels of all the catecholamines...
    20 KB (2,075 words) - 08:55, 17 July 2024
  • Thumbnail for Parkinson's disease
    and end-of-dose motor fluctuations – opicapone, entacapone, and tolcapone. Tolcapone has been available for but its usefulness is limited by possible...
    171 KB (18,711 words) - 19:43, 29 September 2024