NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene. The modification of proteins with ubiquitin is an important cellular...
7 KB (788 words) - 01:42, 17 April 2022
UBE2K NM_005339 UBE2L3 NM_003347 UBE2M NM_003969 Homo sapiens ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) (UBE2M), UBE2N NM_003348 UBE2NL NM_001012989...
48 KB (4,612 words) - 23:41, 12 December 2023
17764 UBE2L5 HGNC:13477 A0A1B0GUS4 17765 UBE2L6 HGNC:12490 O14933 17766 UBE2M HGNC:12491 P61081 17767 UBE2N HGNC:12492 P61088 17768 UBE2NL HGNC:31710...
242 KB (17 words) - 18:43, 6 October 2024
discovered small molecule inhibitors of neddylation E1, neddylation E2 UBE2F and UBE2M-DCN interactions. Tan, M., Zhao, Y., Kim, S. J., Liu, M., Jia, L., Saunders...
10 KB (1,133 words) - 13:43, 23 June 2024
UBE2J2 UBE2K UBE2L3, UBE2L6; (UBE2L1, UBE2L2, UBE2L4 are pseudogenes) UBE2M UBE2N UBE2O UBE2Q1, UBE2Q2 UBE2R1 (CDC34), UBE2R2 UBE2S UBE2T (putative)...
5 KB (605 words) - 04:25, 28 November 2023
form the NEDD8 activation enzyme (E1), then the NEDD8 conjugating enzyme UBE2M or UBE2F (E2), and finally the NEDD8 ligase E3, which will bind the substrate...
4 KB (589 words) - 11:55, 8 October 2024
which resembles ubiquitin, and recruits the catalytic core of the E2 enzyme UBE2M (Ubc12) in a similar manner to that in which ubiquitin interacts with ubiquitin...
10 KB (1,151 words) - 22:25, 3 March 2023
with: AKAP10, AKAP1, AKAP4, ARFGEF1, ARFGEF2, Grb2, MYO7A, PRKAR1B, and UBE2M. cAMP-dependent protein kinase GRCh38: Ensembl release 89: ENSG00000108946...
15 KB (1,841 words) - 15:14, 2 October 2024
has been shown to interact with: Aryl hydrocarbon receptor, NUB1, UBE1C, UBE2M, and UCHL3. ENSG00000285246 GRCh38: Ensembl release 89: ENSG00000129559...
23 KB (2,836 words) - 00:24, 8 May 2024