• The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the...
    24 KB (3,068 words) - 07:21, 7 June 2024
  • [clarification needed] The mammalian MAPK family of kinases includes three subfamilies: Extracellular signal-regulated kinases (ERKs) c-Jun N-terminal kinases (JNKs)...
    46 KB (5,492 words) - 14:52, 20 August 2024
  • Thumbnail for Late endosomal/lysosomal adaptor, mapk and mtor activator 1
    Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 is a protein that in humans is encoded by the LAMTOR1 gene. GRCh38: Ensembl release 89: ENSG00000149357...
    4 KB (542 words) - 02:08, 28 March 2024
  • Thumbnail for Philadelphia chromosome
    important role in maintaining leukemic cell growth and division. The Ras/MAPK/ERK pathway relays signals to nuclear transcription factors and plays a role...
    29 KB (3,538 words) - 15:01, 5 December 2023
  • Thumbnail for IQGAP1
    IQGAP1 (section ERK MAPK)
    signals for proliferation and the actual cellular response. The Ras→Raf→MEK→ERK MAPK signaling pathway plays an integral part in the processes of cell proliferation...
    33 KB (3,922 words) - 20:55, 27 March 2024
  • (MAPK) pathways can induce enzymes such as the COX-2 enzyme. MAPK pathways may also play a role in the regulation of PTGS2. Growth factor MAPK/ERK pathway...
    13 KB (1,750 words) - 10:12, 12 August 2024
  • then functions to allow the MAPK/ERK pathway to progress. Secondly, a protein activated by the MAPK/ERK pathway, called MAPK (mitogen-activated protein...
    62 KB (6,845 words) - 18:30, 22 August 2024
  • Thumbnail for RAGE (receptor)
    PM, Stein U (May 2014). "RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal...
    19 KB (2,337 words) - 03:47, 26 April 2024
  • receptor (mER). It shows sequence homology with ERα and ERβ and activates the MAPK/ERK pathway. The receptor is insensitive to the antiestrogen ICI-182,780 (fulvestrant)...
    2 KB (178 words) - 06:31, 2 November 2023
  • of ATP to cAMP. ERK, a participating protein in the MAPK signaling pathway, can be activated or inhibited by cAMP. cAMP can inhibit ERKs in a variety of...
    16 KB (1,674 words) - 11:49, 16 November 2022