The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the...
24 KB (3,068 words) - 07:21, 7 June 2024
Mitogen-activated protein kinase (redirect from MAPK cascade)
[clarification needed] The mammalian MAPK family of kinases includes three subfamilies: Extracellular signal-regulated kinases (ERKs) c-Jun N-terminal kinases (JNKs)...
46 KB (5,492 words) - 14:52, 20 August 2024
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 is a protein that in humans is encoded by the LAMTOR1 gene. GRCh38: Ensembl release 89: ENSG00000149357...
4 KB (542 words) - 02:08, 28 March 2024
Philadelphia chromosome (section Ras/MAPK/ERK pathway)
important role in maintaining leukemic cell growth and division. The Ras/MAPK/ERK pathway relays signals to nuclear transcription factors and plays a role...
29 KB (3,538 words) - 15:01, 5 December 2023
(MAPK) pathways can induce enzymes such as the COX-2 enzyme. MAPK pathways may also play a role in the regulation of PTGS2. Growth factor MAPK/ERK pathway...
13 KB (1,750 words) - 10:12, 12 August 2024
then functions to allow the MAPK/ERK pathway to progress. Secondly, a protein activated by the MAPK/ERK pathway, called MAPK (mitogen-activated protein...
62 KB (6,845 words) - 18:30, 22 August 2024
PM, Stein U (May 2014). "RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal...
19 KB (2,337 words) - 03:47, 26 April 2024
receptor (mER). It shows sequence homology with ERα and ERβ and activates the MAPK/ERK pathway. The receptor is insensitive to the antiestrogen ICI-182,780 (fulvestrant)...
2 KB (178 words) - 06:31, 2 November 2023
of ATP to cAMP. ERK, a participating protein in the MAPK signaling pathway, can be activated or inhibited by cAMP. cAMP can inhibit ERKs in a variety of...
16 KB (1,674 words) - 11:49, 16 November 2022