mitochondrial is an enzyme that in humans is encoded by the ALDH2 gene located on chromosome 12. ALDH2 belongs to the aldehyde dehydrogenase family of enzymes...
23 KB (2,690 words) - 12:17, 7 September 2024
"Asian flush" or "Asian glow". Around 20–30% of East Asians carry the rs671 (ALDH2*2) allele on chromosome 12, which results in a less functional acetaldehyde...
15 KB (1,659 words) - 13:14, 30 August 2024
In all three classes, constitutive and inducible forms exist. ALDH1 and ALDH2 are the most important enzymes for aldehyde oxidation, and both are tetrameric...
17 KB (2,080 words) - 11:35, 4 April 2024
there are three known genes which encode this enzymatic activity, ALDH1A1, ALDH2, and the more recently discovered ALDH1B1 (also known as ALDH5). These enzymes...
13 KB (1,523 words) - 02:53, 25 May 2024
investigated in native Japanese who have a variant ALDH2 allele termed glu487lys, ALDH2*2 or ALDH2*504lys, which is a single nucleotide polymorphism allele...
16 KB (2,276 words) - 11:24, 25 April 2024
vessels. Individuals that have the ALDH2*2 allele, a variant that has a mutation when compared to the wild-type ALDH2 isozyme, are known to have higher...
20 KB (1,912 words) - 22:19, 23 May 2024
ALDH2*2, and ALDH2*504lys. In the overall Japanese population, about 57% of individuals are homozygous for the normal allele (sometimes termed ALDH2*1)...
48 KB (5,429 words) - 04:39, 26 July 2024
another allele responsible for the flush reaction, the rs671 (ALDH2*2) of the ALDH2 is rare among Europeans and Sub-Saharan Black Africans, while 30%...
25 KB (2,540 words) - 15:11, 20 August 2024
acetate mainly by aldehyde dehydrogenase (ALDH). ALDH2 is an isozyme of ALDH and ALDH2 has a polymorphism (ALDH2*2, Glu487Lys) that makes ADLH2 inactive; this...
26 KB (2,951 words) - 01:10, 18 June 2024
is performed by aldehyde dehydrogenase (ALDH) enzymes. A mutation in the ALDH2 gene that encodes for an inactive or dysfunctional form of this enzyme affects...
106 KB (10,639 words) - 12:25, 16 September 2024