• Thumbnail for ALDH2
    mitochondrial is an enzyme that in humans is encoded by the ALDH2 gene located on chromosome 12. ALDH2 belongs to the aldehyde dehydrogenase family of enzymes...
    23 KB (2,690 words) - 12:17, 7 September 2024
  • Thumbnail for Alcohol flush reaction
    "Asian flush" or "Asian glow". Around 20–30% of East Asians carry the rs671 (ALDH2*2) allele on chromosome 12, which results in a less functional acetaldehyde...
    15 KB (1,659 words) - 13:14, 30 August 2024
  • Thumbnail for Aldehyde dehydrogenase
    In all three classes, constitutive and inducible forms exist. ALDH1 and ALDH2 are the most important enzymes for aldehyde oxidation, and both are tetrameric...
    17 KB (2,080 words) - 11:35, 4 April 2024
  • Thumbnail for Acetaldehyde dehydrogenase
    there are three known genes which encode this enzymatic activity, ALDH1A1, ALDH2, and the more recently discovered ALDH1B1 (also known as ALDH5). These enzymes...
    13 KB (1,523 words) - 02:53, 25 May 2024
  • investigated in native Japanese who have a variant ALDH2 allele termed glu487lys, ALDH2*2 or ALDH2*504lys, which is a single nucleotide polymorphism allele...
    16 KB (2,276 words) - 11:24, 25 April 2024
  • Thumbnail for Alcohol intolerance
    vessels. Individuals that have the ALDH2*2 allele, a variant that has a mutation when compared to the wild-type ALDH2 isozyme, are known to have higher...
    20 KB (1,912 words) - 22:19, 23 May 2024
  • Thumbnail for Short-term effects of alcohol consumption
    ALDH2*2, and ALDH2*504lys. In the overall Japanese population, about 57% of individuals are homozygous for the normal allele (sometimes termed ALDH2*1)...
    48 KB (5,429 words) - 04:39, 26 July 2024
  • another allele responsible for the flush reaction, the rs671 (ALDH2*2) of the ALDH2 is rare among Europeans and Sub-Saharan Black Africans, while 30%...
    25 KB (2,540 words) - 15:11, 20 August 2024
  • Thumbnail for Alcoholic polyneuropathy
    acetate mainly by aldehyde dehydrogenase (ALDH). ALDH2 is an isozyme of ALDH and ALDH2 has a polymorphism (ALDH2*2, Glu487Lys) that makes ADLH2 inactive; this...
    26 KB (2,951 words) - 01:10, 18 June 2024
  • Thumbnail for Ethanol
    is performed by aldehyde dehydrogenase (ALDH) enzymes. A mutation in the ALDH2 gene that encodes for an inactive or dysfunctional form of this enzyme affects...
    106 KB (10,639 words) - 12:25, 16 September 2024