• Thumbnail for BLOSUM
    bioinformatics, the BLOSUM (BLOcks SUbstitution Matrix) matrix is a substitution matrix used for sequence alignment of proteins. BLOSUM matrices are used...
    22 KB (2,553 words) - 08:59, 31 July 2024
  • evolutionary change. The BLOSUM-62 matrix is one of the best substitution matrices for detecting weak protein similarities. BLOSUM matrices with high numbers...
    19 KB (2,483 words) - 14:32, 2 July 2024
  • approximated by compounding small changes that occur over short time scales. The BLOSUM (BLOck SUbstitution Matrix) series of matrices rectifies this problem. Henikoff...
    15 KB (2,105 words) - 07:00, 24 September 2024
  • that the BLOSUM matrices are much more effective. The BLOSUM series were generated by comparing a number of divergent sequences. The BLOSUM series are...
    17 KB (2,564 words) - 04:35, 12 July 2024
  • Thumbnail for Point accepted mutation
    by the BLOSUM matrices. Although both matrices produce similar scoring outcomes they were generated using differing methodologies. The BLOSUM matrices...
    31 KB (4,156 words) - 21:26, 1 April 2024
  • together with his wife Jorja Henikoff, introduced the BLOSUM substitution matrices. The BLOSUM matrices are widely used for sequence alignment of proteins...
    3 KB (221 words) - 11:34, 8 August 2024
  • Thumbnail for Needleman–Wunsch algorithm
    scoring matrices, each with further alterations for specific scenarios: PAM BLOSUM When aligning sequences there are often gaps (i.e. indels), sometimes large...
    25 KB (3,237 words) - 22:44, 16 October 2024
  • became a teacher at St. Friedeswiede. Blosum Pricket (ブロサム=プリケト, Burosamu Puriketo) Voiced by: Hōchū Ōtsuka Blosum Pricket is the Marquis of the town of...
    27 KB (2,142 words) - 15:22, 31 May 2024
  • Thumbnail for Smith–Waterman algorithm
    amino acids is usually more complicated than that of the bases. See PAM, BLOSUM. Gap penalty designates scores for insertion or deletion. A simple gap penalty...
    36 KB (4,659 words) - 19:31, 9 October 2024
  • Thumbnail for Sequence alignment
    amino acid mutations. Another common series of scoring matrices, known as BLOSUM (Blocks Substitution Matrix), encodes empirically derived substitution probabilities...
    56 KB (6,921 words) - 14:05, 31 October 2024