H19 is a gene for a long noncoding RNA, found in humans and elsewhere. H19 has a role in the negative regulation (or limiting) of body weight and cell...

H19 or H-19 may refer to: H19 (gene), a maternally-transmitted human gene British NVC community H19, a type of heath community in the British National...

have hypomethylation of H19 and IGF2. This is thought to lead to low expression of IGF2 and over-expression of the H19 gene. In 10% of the cases, the...

deregulations at H19 imprinted gene in sperm have been observed associated with male infertility. Indeed, methylation loss at H19 imprinted gene has been observed...

and development. They are located on chromosome 11p. Expression of the h19 gene is markedly reduced in both nonfunctioning and functioning adrenal cortical...

of paternal genes. In addition, MTHFR gene promoter hypermethylation has also been associated with methylation loss at H19 imprinted gene in semen samples...

University. Here she identified H19, one of the first imprinted genes. She found that this gene was part of an imprinted gene cluster that included the Insulin-like...

opposite (antisense) to it, often silencing it. In the case of the Ifg2 and H19 genes, CTCF, a transcriptional repressor protein, is involved. CTCF binds to...

Igf2 gene promoter, leaving only the H19 gene to be expressed. When insulator sequences are located in close proximity to the promoter of a gene, it has...

IGF2 and H19 being transcribed from both parental alleles. The protein CTCF is involved in repressing expression of the gene, by binding to the H19 imprinting...