Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a cytoplasmatic protein encoded by gene PTPN22 and a member of PEST family of protein tyrosine...

that certain SNPs in the protein tyrosine phosphatase non-receptor 22 (PTPN22) gene and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) gene can...

analysis. CTLA-4 was confirmed as the main locus for thyroid autoantibodies. PTPN22 is the most recently identified immune-regulatory gene associated with autoimmune...

of susceptibility to lupus erythematosus). In recent studies, the gene PTPN22 has emerged as a significant factor linked to various autoimmune diseases...

genetic factors that predispose disease onset including HLA-B27 and the PTPN22 genotype. Recent evidence has pointed to reactivation of herpes simplex...

transplanted human tissue. One focus of her recent work has been the phosphatase PTPN22, a variant form of which is associated with increased risk of autoimmune...

thyrotropin receptor, protein tyrosine phosphatase nonreceptor type 22 (PTPN22), and cytotoxic T-lymphocyte–associated antigen 4, among others. Since Graves...

ability to develop immune tolerance to insulin, a key autoantigen in T1D. PTPN22: This gene encodes a protein tyrosine phosphatase involved in T-cell receptor...

people with GPA. Several genes involved in the immune system including PTPN22, CTLA4, and human leukocyte antigen genes may influence the risk of developing...

protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (1p13.2 - PTPN22), "CT/TT" genotype showed significant association with anti-topo I. The...