In genetics, trinucleotide repeat disorders, a subset of microsatellite expansion diseases (also known as repeat expansion disorders), are a set of over...

A trinucleotide repeat expansion, also known as a triplet repeat expansion, is the DNA mutation responsible for causing any type of disorder categorized...

severity of symptoms is also noted. Anticipation is common in trinucleotide repeat disorders, such as Huntington's disease and myotonic dystrophy, where...

the most commonly observed manifestations of this process. Trinucleotide repeat disorders also follow a non-Mendelian pattern of inheritance. These diseases...

influenced by the sex of the affected parent. HD is one of several trinucleotide repeat disorders that are caused by the length of a repeated section of a gene...

caused by expanded CAG repeats encoding polyglutamine (polyQ) stretches (see: Trinucleotide repeat disorder). The expanded CAG repeats create an adverse gain-of-function...

(CTG) triplet repeats, termed trinucleotide repeat expansion and classifying DM1 as one of several trinucleotide repeat disorders. This expansion occurs...

disorder in humans. Length changes in other triplet repeats are linked to more than 40 neurological diseases in humans, notably trinucleotide repeat disorders...

disease in the person with the excess number of repeats. Fragile X syndrome, a trinucleotide repeat disorder, is a condition in which premutations may be...

This disorder and finding of fragile X syndrome has an X-linked dominant inheritance. It is typically caused by an expansion of the CGG triplet repeat within...