Tioguanine, also known as thioguanine or 6-thioguanine (6-TG) or tabloid is a medication used to treat acute myeloid leukemia (AML), acute lymphocytic...

analogues subclass of antimetabolites family of medications. It works via 6-thioguanine to disrupt the making of RNA and DNA by cells. Azathioprine was first...

bromodeoxyuridine (BrdU) and a cell lacking HGPRT is resistant to 6-thioguanine (6-TG) and 8-azaguanine. Thus, selection with one of the latter two drugs...

deoxythioguanosine. Some mercaptopurine is converted to nucleotide derivatives of 6-thioguanine (6-TG) by the sequential actions of inosinate (IMP) dehydrogenase and...

providing 6-thioguanine to a subject having said immune-mediated gastrointestinal disorder; and (b) determining the level of 6-thioguanine in said subject...

that are used to treat one or more types of leukemia, include: 6-Mercaptopurine 6-Thioguanine Arsenic trioxide Asparaginase Cladribine Clofarabine Cyclophosphamide...

Such systems include the HPRT assay for resistance to 8-azaguanine or 6-thioguanine, and ouabain-resistance (OUA) assay. Rat primary hepatocytes may also...

mouse BALB/c strain. 4T1 cells are epithelial and are resistant to 6-thioguanine. In preclinical research, 4T1 cells have been used to study breast cancer...

changed the nature of patent law in the United States. 6-Mercaptopurine (6-MP) 6-Thioguanine (6-TG) Azathioprine (AZA) Sahasranaman S, Howard D, Roy S...

olaparib. Combining these newer medicines with older agents such as 6-Thioguanine (6TG) may overcome the resistance that can arise in BRCA cancers to...