during pyroptosis. Pyroptosis, as a form of programmed cell death, has many morphological differences as compared to apoptosis. Both pyroptosis and apoptosis...

signals that lead to Pyroptosis by Caspase-1 are listed below: DNA in the host cytosol binds to AIM2-Like Receptors inducing Pyroptosis Type III secretion...

indicating pyroptosis may in fact be necessary for secretion in some way. Following the inflammatory response, an activated Caspase-1 can induce pyroptosis, a...

Sequential activation of these proteins leads to membrane permeabilization. Pyroptosis is a distinct type of regulated cell death, exhibiting a necrotic morphology...

allow the release of interleukin-1 (IL-1) family cytokines and drive pyroptosis. Several current studies have revealed that GSDMD serves as a specific...

Institutes of Health. Recent studies demonstrated that caspase-1-mediated pyroptosis, a highly inflammatory form of programmed cell death, drives CD4 T-cell...

and innate immune triggers. Historically, inflammatory caspase-mediated pyroptosis  and RIPK-driven necroptosis were described as two major inflammatory...

oxaliplatin and bortezomib, or radiotherapy and photodynamic therapy (PDT). Pyroptosis is a highly inflammatory form of programmed cell death that occurs most...

low levels of CD4+ T cells through a number of mechanisms, including pyroptosis of abortively infected T cells, apoptosis of uninfected bystander cells...

induces pyroptosis. The advances contributed to firmly establishing the sequence of events leading from inflammasome activation to pyroptosis, DAMP release...