In organic chemistry, alkynylation is an addition reaction in which a terminal alkyne (−C≡CH) is added to a carbonyl group (C=O) to form an α-alkynyl alcohol...

SIB-1508Y, also known as Altinicline, a nicotinic receptor agonist. The alkynylation reaction of aryl halides using aromatic acetylenes was reported in 1975...

for methyl ethers and methyl amines. Hydrodealkylation Transalkylation Alkynylation Friedel–Crafts reaction Category:Alkylating agents Category:Ethylating...

ingestion, toxic by skin absorption, and corrosive.[citation needed] Alkynylation Allyl alcohol Propargyl Propargyl chloride NIOSH Pocket Guide to Chemical...

reaction Organolithium reagents Sakurai reaction Indium-mediated allylation Alkynylation Smith, Michael B.; March, Jerry (2007), Advanced Organic Chemistry: Reactions...

Ariana R.; Smith, Joel M. (2021-09-03). "Regioselective Asymmetric Alkynylation of N-Alkyl Pyridiniums". Organic Letters. 23 (17): 6703–6708. doi:10...

expensive alternative reagent is 2-methylbut-3-yn-2-ol, which after alkynylation is deprotected with base. Trimethylsilylacetylene is commercially available...

reaction a pyridine zwitterion in the Hammick reaction an acetylide in alkynylation reactions. a cyanide ion in cyanohydrin reactions In many nucleophilic...

Ludwig Mond discovers nickel carbonyl 1899 John Ulric Nef discovers alkynylation using sodium acetylides. 1909 Paul Ehrlich introduces Salvarsan for the...

with bis(pinacolato)diboron, protonation with i-PrOH, decarboxylative alkynylation with alkynyl carboxylic acids. With tethered cross-coupling partners...