amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. TAAR1 is an intracellular...
59 KB (6,807 words) - 21:42, 17 August 2024
Phenethylamine (category TAAR1 agonists)
monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons...
45 KB (4,443 words) - 21:35, 17 August 2024
Monoamine releasing agent (category TAAR1 agonists)
norepinephrine release in TAAR1 knockout mice. In fact, TAAR1 knockout mice are supersensitive to the effects of amphetamines and TAAR1 activation appears to...
57 KB (4,321 words) - 08:40, 23 August 2024
Tryptamine (category TAAR1 agonists)
changes. It can also weakly activate the trace amine-associated receptor, TAAR1 (hTAAR1 in humans). Limited studies have considered tryptamine to be a trace...
33 KB (2,880 words) - 21:32, 17 August 2024
amine-assorted receptor 1 (TAAR1), a G-Coupled Protein Receptor GPCR, to regulate monoaminergic systems in the brain. Active TAAR1 opposes the autoreceptor's...
8 KB (807 words) - 15:33, 16 April 2024
Phentermine (category TAAR1 agonists)
its parent compound, amphetamine, as they both are TAAR1 agonists, where the activation of TAAR1 in monoamine neurons facilitates the efflux, or release...
20 KB (1,714 words) - 14:14, 6 August 2024
Methamphetamine (category TAAR1 agonists)
has been shown to activate TAAR1 in human astrocytes and generate cAMP as a result. Activation of astrocyte-localized TAAR1 appears to function as a mechanism...
151 KB (14,850 words) - 16:49, 21 August 2024
Tyramine (category TAAR1 agonists)
tyramine, called TAAR1. The TAAR1 receptor is found in the brain, as well as peripheral tissues, including the kidneys. Tyramine binds to TAAR1 as an agonist...
28 KB (2,685 words) - 15:34, 18 August 2024
D2sh–TAAR1 The D2 receptor has been shown to form heterodimers in vitro (and possibly in vivo) with DRD3, DRD5, and 5-HT2A. Prolactin modulator D2sh–TAAR1...
34 KB (3,959 words) - 11:00, 25 July 2024
stimulant effect. There is also evidence suggesting that N,N-DMPEA acts as a TAAR1 agonist in humans, and as a 5-HT1A ligand in rats. Some less conclusive...
6 KB (504 words) - 12:04, 18 May 2024